{"id":"chloraprep-hi-lite-orange","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or erythema"},{"rate":null,"effect":"Contact dermatitis"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The product contains chlorhexidine gluconate, a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, providing rapid and sustained antimicrobial activity. It is applied topically to the surgical site prior to procedures to reduce the microbial load and lower infection risk. The orange dye serves as a visual indicator to ensure complete coverage of the surgical field.","oneSentence":"ChloraPrep Hi-Lite Orange is a chlorhexidine-based antiseptic skin preparation that kills microorganisms on the skin surface to prevent surgical site infections.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:07:10.984Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Surgical site antisepsis and preparation prior to surgical procedures"}]},"trialDetails":[{"nctId":"NCT01968356","phase":"PHASE3","title":"In-vivo Efficacy Study of Patient Preoperative Preps","status":"TERMINATED","sponsor":"Solventum US LLC","startDate":"2013-10","conditions":"Skin Flora Bacterial Reduction Post-product Application","enrollment":171},{"nctId":"NCT01968707","phase":"PHASE3","title":"In-vivo Efficacy Study of Patient Pre-operative Preps","status":"COMPLETED","sponsor":"Solventum US LLC","startDate":"2013-10","conditions":"Bacterial Reduction on Skin Flora Post-product Application","enrollment":426},{"nctId":"NCT03224299","phase":"PHASE2","title":"Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation","status":"COMPLETED","sponsor":"Becton, Dickinson and Company","startDate":"2017-06-21","conditions":"Preoperative Skin Preparation","enrollment":131}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ChloraPrep One-Step","Chlorhexidine gluconate 2% / Isopropyl alcohol 70%","Chlorhexidine gluconate 2% w/v / Isopropyl alcohol 70% v/v","2% CHG / 70% IPA","ChloraPrep"],"phase":"phase_3","status":"active","brandName":"ChloraPrep Hi-Lite Orange","genericName":"ChloraPrep Hi-Lite Orange","companyName":"Solventum US LLC","companyId":"solventum-us-llc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ChloraPrep Hi-Lite Orange is a chlorhexidine-based antiseptic skin preparation that kills microorganisms on the skin surface to prevent surgical site infections. Used for Surgical site antisepsis and preparation prior to surgical procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}