{"id":"chiniofon","rwe":[{"pmid":"7607895","year":"1995","title":"[In vitro and in vivo studies of local disinfection and wound healing].","finding":"","journal":"Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete","studyType":"Clinical Study"},{"pmid":"5355911","year":"1969","title":"[Potentiometric method of quantitative determination of chinosol and chiniofon by means of cupric sulfate].","finding":"","journal":"Farmatsiia","studyType":"Clinical Study"},{"pmid":"13652668","year":"1959","title":"[Treatment of amebic liver abscesses; experiences including therapy of other non-intestinal forms of amebiasis with resotren].","finding":"","journal":"Deutsche medizinische Wochenschrift (1946)","studyType":"Clinical Study"},{"pmid":"13515791","year":"1957","title":"[Treatment of intestinal amoebiasis by a dihalogenated derivative of quinoline.].","finding":"","journal":"Medecine tropicale : revue du Corps de sante colonial","studyType":"Clinical Study"},{"pmid":"13393276","year":"1956","title":"[Management of amebic dysentery and its complications with resotren comp].","finding":"","journal":"Zeitschrift fur Tropenmedizin und Parasitologie","studyType":"Clinical Study"}],"tags":[{"label":"chiniofon","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AX01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["chiniofon"],"offLabel":[],"synonyms":["chiniofon"],"timeline":[],"aiSummary":"CHINIOFON is a small molecule drug in the chiniofon class, but information on its target, approved indications, and commercial status is limited. Its mechanism of action and pharmacokinetic properties are not well-documented. As a result, it is difficult to provide a comprehensive summary of CHINIOFON's characteristics and clinical use. Further research is needed to understand its potential applications and safety profile. Unfortunately, there is not enough information available to provide a detailed summary.","approvals":[],"ecosystem":[],"mechanism":{"target":"Catechol O-methyltransferase","modality":"Small Molecule","drugClass":"chiniofon","explanation":"Imagine CHINIOFON as a key that fits into a lock in the body. When it binds to the lock, it can either turn the key (activating a response) or block the key from turning (inhibiting a response). However, the specific lock and key interaction for CHINIOFON is not well-documented.","oneSentence":"CHINIOFON is thought to work by interacting with a specific biological target, but the exact mechanism is not well understood.","technicalDetail":"CHINIOFON's mechanism of action is likely to involve binding to a specific protein or receptor, but the exact molecular details are not available."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4362","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=CHINIOFON","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CHINIOFON","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:32:33.761485","biosimilars":[],"competitors":[{"drugName":"atovaquone","drugSlug":"atovaquone","fdaApproval":"1992-11-25","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"trimetrexate","drugSlug":"trimetrexate","fdaApproval":"1993-12-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"nitazoxanide","drugSlug":"nitazoxanide","fdaApproval":"2002-11-22","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"chiniofon","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"atovaquone","brandName":"atovaquone","genericName":"atovaquone","approvalYear":"1992","relationship":"same-class"},{"drugId":"trimetrexate","brandName":"trimetrexate","genericName":"trimetrexate","approvalYear":"1993","relationship":"same-class"},{"drugId":"nitazoxanide","brandName":"nitazoxanide","genericName":"nitazoxanide","approvalYear":"2002","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT01851642","phase":"","title":"Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs","status":"RECRUITING","sponsor":"University of Florida","startDate":"2007-08-09","conditions":["Alpha-1 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S.A. de C.V.","startDate":"2021-11-29","conditions":["Seborrheic Dermatitis","Psoriasis of Scalp"],"enrollment":90,"completionDate":"2022-02-25"},{"nctId":"NCT01899144","phase":"PHASE2","title":"Efficacy and Safety Comparison of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients","status":"COMPLETED","sponsor":"Teva Branded Pharmaceutical Products R&D, Inc.","startDate":"2013-07","conditions":["Asthma"],"enrollment":61,"completionDate":"2013-10"},{"nctId":"NCT02513160","phase":"PHASE3","title":"Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma","status":"COMPLETED","sponsor":"Teva Branded Pharmaceutical Products R&D, Inc.","startDate":"2015-09-30","conditions":["Persistent Asthma"],"enrollment":713,"completionDate":"2016-03-31"},{"nctId":"NCT01429701","phase":"PHASE3","title":"Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in 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