{"id":"chining-decoction","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a decoction (herbal extract), ChiNing combines multiple botanical ingredients traditionally used in Chinese oncology practice. The formulation is believed to work through immunomodulation, promoting anti-tumor immunity, and potentially inhibiting angiogenesis and tumor cell proliferation. The exact molecular mechanisms remain incompletely characterized but likely involve polysaccharides, alkaloids, and other phytochemicals present in the constituent herbs.","oneSentence":"ChiNing decoction is a traditional Chinese medicine formulation that enhances immune function and inhibits tumor growth through multi-component herbal synergy.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:05:41.096Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cancer (specific indication type not publicly detailed; Phase 3 trial context suggests solid tumors or hematologic malignancy)"}]},"trialDetails":[{"nctId":"NCT02303197","phase":"PHASE3","title":"Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis","status":"COMPLETED","sponsor":"Tianjin Medical University Cancer Institute and Hospital","startDate":"2014-05","conditions":"Head and Neck Cancer","enrollment":70}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Addition and subtraction of Liangge San"],"phase":"phase_3","status":"active","brandName":"ChiNing decoction","genericName":"ChiNing decoction","companyName":"Tianjin Medical University Cancer Institute and Hospital","companyId":"tianjin-medical-university-cancer-institute-and-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ChiNing decoction is a traditional Chinese medicine formulation that enhances immune function and inhibits tumor growth through multi-component herbal synergy. Used for Cancer (specific indication type not publicly detailed; Phase 3 trial context suggests solid tumors or hematologic malignancy).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}