{"id":"cfnb-posterior-capsular-injection","safety":{"commonSideEffects":[{"rate":null,"effect":"Corneal edema"},{"rate":null,"effect":"Anterior chamber inflammation"},{"rate":null,"effect":"Transient vision disturbance"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This combination therapy involves intracameral or posterior capsular injection of a fortified antimicrobial formulation to prevent endophthalmitis and reduce inflammation following cataract surgery. The posterior capsular delivery route ensures high local concentrations at the site of surgical trauma while minimizing systemic exposure.","oneSentence":"CFNB (Cyclopentolate Fortified Neomycin B) with posterior capsular injection delivers antimicrobial and anti-inflammatory agents directly to the posterior segment of the eye during cataract surgery.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:29:17.917Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prophylaxis of endophthalmitis in cataract surgery"},{"name":"Reduction of post-operative inflammation following cataract extraction"}]},"trialDetails":[{"nctId":"NCT00869037","phase":"PHASE4","title":"Analgesia After Total Knee Arthroplasty","status":"UNKNOWN","sponsor":"University of Manitoba","startDate":"2009-03","conditions":"Analgesia","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"CFNB + Posterior Capsular Injection","genericName":"CFNB + Posterior Capsular Injection","companyName":"University of Manitoba","companyId":"university-of-manitoba","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CFNB (Cyclopentolate Fortified Neomycin B) with posterior capsular injection delivers antimicrobial and anti-inflammatory agents directly to the posterior segment of the eye during cataract surgery. Used for Prophylaxis of endophthalmitis in cataract surgery, Reduction of post-operative inflammation following cataract extraction.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}