{"id":"cetearyl-alcohol-lotion","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation"},{"rate":null,"effect":"Contact dermatitis"},{"rate":null,"effect":"Folliculitis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cetearyl alcohol is a fatty alcohol that functions as an emulsifier and thickening agent in topical formulations. It helps to occlude the skin, preventing transepidermal water loss and maintaining skin hydration. This mechanism makes it useful for managing dry skin conditions and maintaining skin barrier integrity.","oneSentence":"Cetearyl alcohol acts as an emollient and skin protectant that forms a protective barrier on the skin surface to reduce water loss and soothe irritated skin.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:43:24.872Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry skin and xerosis"},{"name":"Skin irritation and inflammation"}]},"trialDetails":[{"nctId":"NCT06125912","phase":"NA","title":"A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging","status":"COMPLETED","sponsor":"Dime Beauty Co.","startDate":"2023-09-25","conditions":"Skin Aging","enrollment":35},{"nctId":"NCT06146712","phase":"NA","title":"A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity","status":"COMPLETED","sponsor":"Asutra","startDate":"2023-08-07","conditions":"Sleep","enrollment":35},{"nctId":"NCT00754247","phase":"PHASE4","title":"A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars","status":"COMPLETED","sponsor":"University of Miami","startDate":"2006-03","conditions":"Keloid, Hypertrophic Scar, Cicatrix, Hypertrophic","enrollment":30},{"nctId":"NCT00693654","phase":"PHASE4","title":"Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients","status":"COMPLETED","sponsor":"Wake Forest University","startDate":"2006-11","conditions":"Pruritis","enrollment":28}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Cetaphil lotion"],"phase":"marketed","status":"active","brandName":"Cetearyl alcohol lotion","genericName":"Cetearyl alcohol lotion","companyName":"University of Miami","companyId":"university-of-miami","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cetearyl alcohol acts as an emollient and skin protectant that forms a protective barrier on the skin surface to reduce water loss and soothe irritated skin. Used for Dry skin and xerosis, Skin irritation and inflammation.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}