{"id":"cervavac-as-three-dose-regimen","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, erythema, swelling)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Myalgia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cervavac is designed to induce cellular and humoral immune responses against HPV-infected cells, particularly those expressing HPV16 and HPV18 antigens that are associated with cervical cancer development. As a therapeutic vaccine administered in a three-dose regimen, it aims to boost the body's own immune system to recognize and destroy existing HPV-positive lesions and cancer cells, rather than prevent initial infection like prophylactic HPV vaccines.","oneSentence":"Cervavac is a therapeutic HPV vaccine that stimulates the immune system to target and eliminate cervical cancer cells expressing human papillomavirus antigens.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:05:21.093Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cervical cancer (therapeutic indication)"},{"name":"HPV-associated cervical intraepithelial neoplasia"}]},"trialDetails":[{"nctId":"NCT06281119","phase":"PHASE3","title":"Clinical Study to Evaluate SIIPL QHPV Vaccine (CERVAVAC®) in Women Living with HIV Aged 15-25 Years","status":"NOT_YET_RECRUITING","sponsor":"Serum Institute of India Pvt. Ltd.","startDate":"2025-03","conditions":"Human Papillomavirus Infection","enrollment":450}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Cervavac as three dose regimen","genericName":"Cervavac as three dose regimen","companyName":"Serum Institute of India Pvt. Ltd.","companyId":"serum-institute-of-india-pvt-ltd","modality":"Biologic","firstApprovalDate":"","aiSummary":"Cervavac is a therapeutic HPV vaccine that stimulates the immune system to target and eliminate cervical cancer cells expressing human papillomavirus antigens. Used for Cervical cancer (therapeutic indication), HPV-associated cervical intraepithelial neoplasia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}