{"id":"cefuroxime-pivoxetil","rwe":[{"pmid":"34803447","year":"2021","title":"Binary-QSAR guided virtual screening of FDA approved drugs and compounds in clinical investigation against SARS-CoV-2 main protease.","finding":"","journal":"Turkish journal of biology = Turk biyoloji dergisi","studyType":"Clinical Study"}],"tags":[{"label":"Cephalosporin Antibacterial","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["cefuroxime pivoxetil"],"offLabel":[],"synonyms":["cefuroxime pivoxetil"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Cephalosporin Antibacterial","explanation":"Imagine your body's cells are like houses, and the bacterial cell wall is like the foundation. Cefuroxime pivoxetil blocks the construction of this foundation, making it impossible for the bacteria to build a strong wall and ultimately leading to their death.","oneSentence":"Cefuroxime pivoxetil works by inhibiting the bacterial enzyme responsible for cell wall synthesis, ultimately leading to bacterial cell death.","technicalDetail":"Cefuroxime pivoxetil exerts its antibacterial effect by competitively inhibiting the action of the bacterial enzyme transpeptidase, which is essential for the cross-linking of peptidoglycan chains in the bacterial cell wall."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/567","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cefuroxime pivoxetil","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:29:47.637391","biosimilars":[],"competitors":[],"genericName":"cefuroxime pivoxetil","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"d00056","NDDF":"003590","UNII":"LR90117565","CHEBI":"CHEBI:3515","VANDF":"4019668","INN_ID":"3902","RXNORM":"2194","UMLSCUI":"C2699152","ChEMBL_ID":"CHEMBL1697786","KEGG_DRUG":"D03431","DRUGBANK_ID":"DB01112","PDB_CHEM_ID":" KOV","PUBCHEM_CID":"6321417","SNOMEDCT_US":"372833007","MESH_DESCRIPTOR_UI":"D002444"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[{"date":"2021","pmid":"34803447","title":"Binary-QSAR guided virtual screening of FDA approved drugs and compounds in clinical investigation against SARS-CoV-2 main protease.","journal":"Turkish journal of biology = Turk biyoloji dergisi"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"cefuroxime pivoxetil","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Cefuroxime pivoxetil is a small molecule antibiotic. It is also known by the synonyms CCI 23628, CCI-23628, and CEFUROXIME PIVOXETIL.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}