{"id":"cefteram-pivoxil","rwe":[{"pmid":"32889346","year":"2020","title":"Impurity profiling of Cefteram pivoxil based on Fourier transform ion cyclotron resonance MS.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"},{"pmid":"30233195","year":"2018","title":"Drug-induced tubulointerstitial nephritis in a retrospective study using spontaneous reporting system database.","finding":"","journal":"Therapeutics and clinical risk management","studyType":"Clinical Study"},{"pmid":"21461254","year":"2011","title":"New sensitization to house dust mites in cefteram-induced occupational asthma: a case report.","finding":"","journal":"Allergy, asthma & immunology research","studyType":"Clinical Study"},{"pmid":"20166432","year":"2009","title":"Pharmacokinetics and bioequivalence studies of cefteram pivoxil in healthy Chinese volunteers.","finding":"","journal":"European journal of drug metabolism and pharmacokinetics","studyType":"Clinical Study"},{"pmid":"19673352","year":"2009","title":"[Evaluation of antimicrobial prophylaxis after normal delivery].","finding":"","journal":"The Japanese journal of antibiotics","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tomiron","offLabel":[],"synonyms":["cefteram pivoxil","tomiron"],"timeline":[],"approvals":[],"brandName":"Tomiron","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine bacteria as tiny factories that build their own walls to protect themselves. Tomiron blocks the machines that make these walls, causing the bacteria to die. This helps to treat infections caused by these bacteria.","oneSentence":"Tomiron works by stopping bacteria from building their cell walls, ultimately leading to their death.","technicalDetail":"Tomiron (cefteram pivoxil) exerts its antibacterial effect by competitively inhibiting the transpeptidase activity of penicillin-binding proteins (PBPs), which are essential for bacterial cell wall synthesis."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/560","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cefteram pivoxil","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:26:35.970744","biosimilars":[],"competitors":[],"genericName":"cefteram pivoxil","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008157","UNII":"0OD86RT58C","CHEBI":"CHEBI:31381","INN_ID":"5947","UMLSCUI":"C0108947","ChEMBL_ID":"CHEMBL2105953","KEGG_DRUG":"D01686","PUBCHEM_CID":"5362114","MESH_SUPPLEMENTAL_RECORD_UI":"C046817"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":49,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[{"date":"2020 Nov 30","pmid":"32889346","title":"Impurity profiling of Cefteram pivoxil based on Fourier transform ion cyclotron resonance MS.","journal":"Journal of pharmaceutical and biomedical analysis"},{"date":"2018","pmid":"30233195","title":"Drug-induced tubulointerstitial nephritis in a retrospective study using spontaneous reporting system database.","journal":"Therapeutics and clinical risk management"},{"date":"2011 Apr","pmid":"21461254","title":"New sensitization to house dust mites in cefteram-induced occupational asthma: a case report.","journal":"Allergy, asthma & immunology research"},{"date":"2009 Jul-Sep","pmid":"20166432","title":"Pharmacokinetics and bioequivalence studies of cefteram pivoxil in healthy Chinese volunteers.","journal":"European journal of drug metabolism and pharmacokinetics"},{"date":"2009 Apr","pmid":"19673352","title":"[Evaluation of antimicrobial prophylaxis after normal delivery].","journal":"The Japanese journal of antibiotics"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Tomiron, also known as Cefteram, is a third-generation cephalosporin antibiotic. It is a small molecule modality.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}