{"id":"cefteram","rwe":[{"pmid":"32889346","year":"2020","title":"Impurity profiling of Cefteram pivoxil based on Fourier transform ion cyclotron resonance MS.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"},{"pmid":"30233195","year":"2018","title":"Drug-induced tubulointerstitial nephritis in a retrospective study using spontaneous reporting system database.","finding":"","journal":"Therapeutics and clinical risk management","studyType":"Clinical Study"},{"pmid":"27250799","year":"2016","title":"Preparation of Fine Particles with Improved Solubility Using a Complex Fluidized-Bed Granulator Equipped with a Particle-Sizing Mechanism.","finding":"","journal":"Chemical & pharmaceutical bulletin","studyType":"Clinical Study"},{"pmid":"26625536","year":"2015","title":"[Sensitivity surveillance of Streptococcus pneumoniae isolates for several antibacterial agents in Gifu and Aichi prefectures (2011-2012)].","finding":"","journal":"The Japanese journal of antibiotics","studyType":"Clinical Study"},{"pmid":"25618776","year":"2015","title":"Nationwide survey of the development of drug resistance in the pediatric field in 2007, 2010, and 2012: drug sensitivity of Haemophilus influenzae serotype b strain in Japan.","finding":"","journal":"Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"J01DD18","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ceftetrame","offLabel":[],"synonyms":["cefteram","cefterame","ceftetrame"],"timeline":[],"approvals":[],"brandName":"Ceftetrame","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine Ceftetrame as a key that fits into a lock in the body. When it binds to its target, it helps to turn off or turn on specific cellular processes that are involved in the disease. This can help to restore balance and promote healing.","oneSentence":"Ceftetrame is a small molecule that works by binding to specific biological targets to produce its therapeutic effect.","technicalDetail":"Ceftetrame's mechanism of action is not well understood, but it is likely to involve the inhibition of a specific enzyme or receptor, leading to changes in cellular signaling pathways and ultimately, therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3076","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CEFTERAM","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:29:00.358271","biosimilars":[],"competitors":[{"drugName":"cefotaxime","drugSlug":"cefotaxime","fdaApproval":"1981-03-11","genericCount":10,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ceftazidime","drugSlug":"ceftazidime","fdaApproval":"1985-07-19","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ceftriaxone","drugSlug":"ceftriaxone","fdaApproval":"1984-12-21","genericCount":26,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"cefmenoxime","drugSlug":"cefmenoxime","fdaApproval":"1987-12-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"latamoxef","drugSlug":"latamoxef","fdaApproval":"","relationship":"same-class"},{"drugName":"ceftizoxime","drugSlug":"ceftizoxime","fdaApproval":"1983-09-15","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"cefixime","drugSlug":"cefixime","fdaApproval":"1989-04-28","patentExpiry":"Dec 14, 2028","patentStatus":"Patent 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pivoxil","drugSlug":"cefditoren-pivoxil","fdaApproval":"2001-08-29","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"cefteram","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"cefotaxime","brandName":"cefotaxime","genericName":"cefotaxime","approvalYear":"1981","relationship":"same-class"},{"drugId":"ceftazidime","brandName":"ceftazidime","genericName":"ceftazidime","approvalYear":"1985","relationship":"same-class"},{"drugId":"ceftriaxone","brandName":"ceftriaxone","genericName":"ceftriaxone","approvalYear":"1984","relationship":"same-class"},{"drugId":"cefmenoxime","brandName":"cefmenoxime","genericName":"cefmenoxime","approvalYear":"1987","relationship":"same-class"},{"drugId":"latamoxef","brandName":"latamoxef","genericName":"latamoxef","approvalYear":"","relationship":"same-class"},{"drugId":"ceftizoxime","brandName":"ceftizoxime","genericName":"ceftizoxime","approvalYear":"1983","relationship":"same-class"},{"drugId":"cefixime","brandName":"cefixime","genericName":"cefixime","approvalYear":"1989","relationship":"same-class"},{"drugId":"cefpiramide","brandName":"cefpiramide","genericName":"cefpiramide","approvalYear":"1989","relationship":"same-class"},{"drugId":"cefoperazone","brandName":"cefoperazone","genericName":"cefoperazone","approvalYear":"1982","relationship":"same-class"},{"drugId":"cefpodoxime-proxetil","brandName":"cefpodoxime proxetil","genericName":"cefpodoxime proxetil","approvalYear":"1992","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008157","UNII":"74CQ4Q3N63","CHEBI":"CHEBI:135776","INN_ID":"5947","UMLSCUI":"C0108946","ChEMBL_ID":"CHEMBL2105953","KEGG_DRUG":"D07655","PUBCHEM_CID":"6537431","IUPHAR_LIGAND_ID":"11051","MESH_SUPPLEMENTAL_RECORD_UI":"C049493"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":97,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"J01DD18","allCodes":["J01DD18"]},"biosimilarFilings":[],"recentPublications":[{"date":"2020 Nov 30","pmid":"32889346","title":"Impurity profiling of Cefteram pivoxil based on Fourier transform ion cyclotron resonance MS.","journal":"Journal of pharmaceutical and biomedical analysis"},{"date":"2018","pmid":"30233195","title":"Drug-induced tubulointerstitial nephritis in a retrospective study using spontaneous reporting system database.","journal":"Therapeutics and clinical risk management"},{"date":"2016","pmid":"27250799","title":"Preparation of Fine Particles with Improved Solubility Using a Complex Fluidized-Bed Granulator Equipped with a Particle-Sizing Mechanism.","journal":"Chemical & pharmaceutical bulletin"},{"date":"2015 Aug","pmid":"26625536","title":"[Sensitivity surveillance of Streptococcus pneumoniae isolates for several antibacterial agents in Gifu and Aichi prefectures (2011-2012)].","journal":"The Japanese journal of antibiotics"},{"date":"2015 Apr","pmid":"25618776","title":"Nationwide survey of the development of drug resistance in the pediatric field in 2007, 2010, and 2012: drug sensitivity of Haemophilus influenzae serotype b strain in Japan.","journal":"Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ceftetrame is a small molecule antibiotic. It is also known by the synonyms Ceftetrame, Ceftetrame, Ceftetrame pivoxil, and RO 19-5247.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}