{"id":"cefalexin-pivoxil","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"pivalexin","offLabel":[],"synonyms":["pivalexin","pivcephalexin","cefalexin pivoxil"],"timeline":[],"brandName":"Pivalexin","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like buildings. Bacteria are like construction workers that build their own cells. Cefalexin, the active form of pivalexin, is like a construction inspector that stops the bacteria from building their cells, ultimately killing them.","oneSentence":"Pivalexin works by being converted into cefalexin in the body, which then inhibits bacterial cell wall synthesis.","technicalDetail":"Cefalexin pivoxil is a prodrug that undergoes hydrolysis in the body to form cefalexin, a first-generation cephalosporin antibiotic that exerts its antibacterial effects by inhibiting the synthesis of peptidoglycan, a critical component of bacterial cell walls."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2217","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cefalexin pivoxil","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:16:54.374690","biosimilars":[],"competitors":[],"genericName":"cefalexin pivoxil","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"d00096","NDDF":"002716","UNII":"H2Q6O02R95","CHEBI":"CHEBI:135750","VANDF":"4018891","RXNORM":"2231","UMLSCUI":"C0137146","DRUGBANK_ID":"DB00567","PUBCHEM_CID":"20055002","SNOMEDCT_US":"387304003","MESH_SUPPLEMENTAL_RECORD_UI":"C014253"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":25,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Pivalexin is a small molecule inhibitor of bacterial penicillin-binding protein. It is classified as an inhibitor of the drug class, with a mechanism of action as a bacterial penicillin-binding protein inhibitor.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}