{"id":"cefadroxil-tablets-manufactured-by-gsk","safety":{"commonSideEffects":[{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Hypersensitivity reactions"},{"rate":null,"effect":"Rash"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cefadroxil is a first-generation cephalosporin antibiotic that works by disrupting the formation of bacterial cell walls. It binds to penicillin-binding proteins and prevents cross-linking of peptidoglycan, leading to cell wall instability and bacterial cell lysis. This bactericidal mechanism is effective against a broad spectrum of gram-positive and some gram-negative bacteria.","oneSentence":"Cefadroxil inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and cross-linking peptidoglycan strands.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:29:50.935Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bacterial infections caused by susceptible organisms including skin and soft tissue infections"},{"name":"Urinary tract infections"},{"name":"Respiratory tract infections"},{"name":"Streptococcal pharyngitis"}]},"trialDetails":[{"nctId":"NCT02446496","phase":"PHASE4","title":"A Bioequivalence Study of Cefadroxil Film Coated Tablets After A Single Oral Dose Administration to Healthy Subjects","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2014-03-31","conditions":"Infections, Urinary Tract","enrollment":24}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Cefadroxil tablets manufactured by GSK","genericName":"Cefadroxil tablets manufactured by GSK","companyName":"GlaxoSmithKline","companyId":"gsk","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cefadroxil inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and cross-linking peptidoglycan strands. Used for Bacterial infections caused by susceptible organisms including skin and soft tissue infections, Urinary tract infections, Respiratory tract infections.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}