{"id":"cd07805-47-gel-0-5-cd07805-47-vehicle","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Dryness"},{"rate":null,"effect":"Peeling"}]},"_chembl":{"chemblId":"CHEMBL3662273","moleculeType":"Small molecule","molecularWeight":"469.55"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"CD07805/47 is a selective retinoid compound designed for topical application. It binds to retinoid receptors in the skin, promoting keratinocyte differentiation and reducing inflammatory responses. The gel formulation is optimized for dermal penetration while the vehicle control allows for efficacy comparison in clinical trials.","oneSentence":"CD07805/47 is a topical retinoid that modulates retinoid receptor signaling to reduce inflammation and promote skin cell differentiation in dermatological conditions.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:05:02.829Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acne vulgaris"},{"name":"Photoaging/photodamaged skin"}]},"trialDetails":[{"nctId":"NCT01659853","phase":"PHASE3","title":"Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea","status":"COMPLETED","sponsor":"Galderma R&D","startDate":"2012-09","conditions":"Erythema, Rosacea","enrollment":70},{"nctId":"NCT01174030","phase":"PHASE2","title":"Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea","status":"COMPLETED","sponsor":"Galderma R&D","startDate":"2010-08","conditions":"Rosacea","enrollment":269},{"nctId":"NCT00989014","phase":"PHASE2","title":"Dose-Finding Study of CD07805/47 Topical Gel in Subjects With Erythematotelangiectatic Rosacea","status":"COMPLETED","sponsor":"Galderma R&D","startDate":"2009-09","conditions":"Erythematotelangiectatic Rosacea","enrollment":122}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":11,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["brimonidine tartrate gel 0.5%","brimonidine tartrate gel vehicle"],"phase":"phase_3","status":"active","brandName":"CD07805/47 gel 0.5%/CD07805/47 Vehicle","genericName":"CD07805/47 gel 0.5%/CD07805/47 Vehicle","companyName":"Galderma R&D","companyId":"galderma-r-d","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CD07805/47 is a topical retinoid that modulates retinoid receptor signaling to reduce inflammation and promote skin cell differentiation in dermatological conditions. Used for Acne vulgaris, Photoaging/photodamaged skin.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}