{"id":"cb-183-315","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL1165603","moleculeType":"Small molecule","molecularWeight":"725.68"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"CB-183,315 inhibits bacterial protein synthesis through a novel mechanism of action targeting gram-positive bacteria. The drug is designed to overcome resistance mechanisms seen with existing antibiotics. It represents a new class of antibacterial agents developed to address unmet needs in serious gram-positive infections.","oneSentence":"CB-183,315 is a selective inhibitor of bacterial protein synthesis that targets gram-positive pathogens by binding to the bacterial ribosome.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:05:00.776Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Gram-positive bacterial infections (phase 3 development)"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":11,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Surotomycin"],"phase":"phase_3","status":"active","brandName":"CB-183,315","genericName":"CB-183,315","companyName":"Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)","companyId":"cubist-pharmaceuticals-llc-a-subsidiary-of-merck-co-inc-rahway-new-jersey-usa","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CB-183,315 is a selective inhibitor of bacterial protein synthesis that targets gram-positive pathogens by binding to the bacterial ribosome. Used for Gram-positive bacterial infections (phase 3 development).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":2,"withResults":2},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}