{"id":"carbuterol","rwe":[{"pmid":"41554531","year":"2026","title":"Veterinary Drug Residues in Animal-Origin Food: a UPLC-MS/MS Screening Method for the Determination of 21 Beta-Agonists in Animal Lung and Liver According to Commission Implementing Regulation (EU) 2021/808.","finding":"","journal":"Journal of mass spectrometry : JMS","studyType":"Clinical Study"},{"pmid":"35091293","year":"2022","title":"An ultrasensitive colloidal gold immunosensor to simultaneously detect 12 beta (2)-adrenergic agonists.","finding":"","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences","studyType":"Clinical Study"},{"pmid":"25476312","year":"2015","title":"Immobilized β-cyclodextrin-based silica vs polymer monoliths for chiral nano liquid chromatographic separation of racemates.","finding":"","journal":"Talanta","studyType":"Clinical Study"},{"pmid":"24604679","year":"2014","title":"Enantioselective nano liquid chromatographic separation of racemic pharmaceuticals: a facile one-pot in situ preparation of lipase-based polymer monoliths in capillary format.","finding":"","journal":"Chirality","studyType":"Clinical Study"},{"pmid":"19058164","year":"2009","title":"Hydrophobicity-aided potentiometric detection of catecholamines, beta-agonists, and beta-blockers in a mixed-solvent capillary electrophoresis system.","finding":"","journal":"Journal of separation science","studyType":"Clinical Study"}],"tags":[{"label":"carbuterol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R03AC10","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["carbuterol hydrochloride","carbuterol","carbuterol HCl"],"offLabel":[],"synonyms":["carbuterol hydrochloride","carbuterol","carbuterol HCl"],"timeline":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"carbuterol","explanation":"Imagine your airways are like a narrow road that gets congested when you're sick. Carbuterol helps to relax the muscles around the road, making it easier to breathe by widening the airway.","oneSentence":"Carbuterol works by stimulating the beta-2 adrenergic receptors in the lungs to relax airway smooth muscle and improve breathing.","technicalDetail":"Carbuterol acts as a beta-2 adrenergic receptor agonist, activating the Gs protein-coupled receptor to increase intracellular cAMP levels, leading to relaxation of airway smooth muscle and bronchodilation."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/506","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CARBUTEROL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:10:31.860004","biosimilars":[],"competitors":[{"drugName":"salbutamol","drugSlug":"salbutamol","fdaApproval":"1981-05-01","relationship":"same-class"},{"drugName":"terbutaline","drugSlug":"terbutaline","fdaApproval":"1974-03-25","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"isoetarine","drugSlug":"isoetarine","fdaApproval":"1979-10-23","relationship":"same-class"},{"drugName":"pirbuterol","drugSlug":"pirbuterol","fdaApproval":"1986-12-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"salmeterol","drugSlug":"salmeterol","fdaApproval":"1994-02-04","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"formoterol","drugSlug":"formoterol","fdaApproval":"2001-02-16","genericCount":10,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"clenbuterol","drugSlug":"clenbuterol","fdaApproval":"","relationship":"same-class"},{"drugName":"bitolterol","drugSlug":"bitolterol","fdaApproval":"1984-12-28","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"indacaterol","drugSlug":"indacaterol","fdaApproval":"2011-07-01","patentExpiry":"Oct 11, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"olodaterol","drugSlug":"olodaterol","fdaApproval":"2014-07-31","patentExpiry":"Jan 19, 2027","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"carbuterol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"salbutamol","brandName":"salbutamol","genericName":"salbutamol","approvalYear":"1981","relationship":"same-class"},{"drugId":"terbutaline","brandName":"terbutaline","genericName":"terbutaline","approvalYear":"1974","relationship":"same-class"},{"drugId":"isoetarine","brandName":"isoetarine","genericName":"isoetarine","approvalYear":"1979","relationship":"same-class"},{"drugId":"pirbuterol","brandName":"pirbuterol","genericName":"pirbuterol","approvalYear":"1986","relationship":"same-class"},{"drugId":"salmeterol","brandName":"salmeterol","genericName":"salmeterol","approvalYear":"1994","relationship":"same-class"},{"drugId":"formoterol","brandName":"formoterol","genericName":"formoterol","approvalYear":"2001","relationship":"same-class"},{"drugId":"clenbuterol","brandName":"clenbuterol","genericName":"clenbuterol","approvalYear":"","relationship":"same-class"},{"drugId":"bitolterol","brandName":"bitolterol","genericName":"bitolterol","approvalYear":"1984","relationship":"same-class"},{"drugId":"indacaterol","brandName":"indacaterol","genericName":"indacaterol","approvalYear":"2011","relationship":"same-class"},{"drugId":"olodaterol","brandName":"olodaterol","genericName":"olodaterol","approvalYear":"2014","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006835","UNII":"0N12JR32MR","CHEBI":"CHEBI:135100","INN_ID":"3360","UMLSCUI":"C0054773","ChEMBL_ID":"CHEMBL2110780","KEGG_DRUG":"D03402","DRUGBANK_ID":"DB13625","PUBCHEM_CID":"36976","SECONDARY_CAS_RN":"34866-46-1","MESH_SUPPLEMENTAL_RECORD_UI":"C100249"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":44,"therapeuticAreas":["Respiratory"],"atcClassification":{"source":"DrugCentral","atcCode":"R03AC10","allCodes":["R03AC10","R03CC10"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Feb","pmid":"41554531","title":"Veterinary Drug Residues in Animal-Origin Food: a UPLC-MS/MS Screening Method for the Determination of 21 Beta-Agonists in Animal Lung and Liver According to Commission Implementing Regulation (EU) 2021/808.","journal":"Journal of mass spectrometry : JMS"},{"date":"2022 Feb 15","pmid":"35091293","title":"An ultrasensitive colloidal gold immunosensor to simultaneously detect 12 beta (2)-adrenergic agonists.","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences"},{"date":"2015 Jan","pmid":"25476312","title":"Immobilized β-cyclodextrin-based silica vs polymer monoliths for chiral nano liquid chromatographic separation of racemates.","journal":"Talanta"},{"date":"2014 Nov","pmid":"24604679","title":"Enantioselective nano liquid chromatographic separation of racemic pharmaceuticals: a facile one-pot in situ preparation of lipase-based polymer monoliths in capillary format.","journal":"Chirality"},{"date":"2009 Jan","pmid":"19058164","title":"Hydrophobicity-aided potentiometric detection of catecholamines, beta-agonists, and beta-blockers in a mixed-solvent capillary electrophoresis system.","journal":"Journal of separation science"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"CARBUTEROL","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Carbuterol is a small molecule drug in the carbuterol class, but specific details about its development, approval status, and commercial status are not available. It is intended to treat a specific condition, but the target and approved indications are unknown. As a small molecule, carbuterol works by interacting with specific biological targets to produce a therapeutic effect. The safety considerations and pharmacokinetic properties of carbuterol are also not well-documented. Further research is needed to fully understand the properties and potential uses of this drug.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}