{"id":"carbocromen","rwe":[{"pmid":"8601429","year":"1996","title":"Antioxidants differentially affect nuclear factor kappa B-mediated nitric oxide synthase expression in vascular smooth muscle cells.","finding":"","journal":"FEBS letters","studyType":"Clinical Study"},{"pmid":"1991345","year":"1991","title":"Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts.","finding":"","journal":"Circulation research","studyType":"Clinical Study"},{"pmid":"2201083","year":"1990","title":"Drug test value by transcranial Doppler in the diagnosis of neurologic vascular diseases.","finding":"","journal":"Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie","studyType":"Clinical Study"},{"pmid":"3285823","year":"1988","title":"Decreased coronary vascular reserve in Watanabe heritable hyperlipidemic rabbits.","finding":"","journal":"Arteriosclerosis (Dallas, Tex.)","studyType":"Clinical Study"},{"pmid":"2410706","year":"1985","title":"Cardioprotective effects of carbocromen in awake and anesthetized dogs with amitriptyline poisoning.","finding":"","journal":"Journal of cardiovascular pharmacology","studyType":"Clinical Study"}],"tags":[{"label":"carbocromen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C01DX05","category":"atc"},{"label":"Active","category":"status"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Vasodilator Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"chromonar","offLabel":[],"synonyms":["carbocromen","carbochromen","carbochromene","chromonar","chromonar hydrochloride","chromonar HCl","carbocromene"],"timeline":[],"brandName":"Chromonar","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"carbocromen","explanation":"Imagine your cells are like containers holding important chemicals. Chromonar helps keep these containers closed, so the chemicals don't leak out and cause problems. This can help prevent certain conditions from developing or getting worse.","oneSentence":"Chromonar works by stabilizing cell membranes to prevent the release of certain chemicals.","technicalDetail":"Chromonar is believed to exert its effects by modulating the activity of ion channels and stabilizing the cell membrane, although the exact molecular mechanisms are not well understood."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3098","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=carbocromen","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:11:49.218246","biosimilars":[],"competitors":[{"drugName":"nesiritide","drugSlug":"nesiritide","fdaApproval":"2001-08-10","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"vericiguat","drugSlug":"vericiguat","fdaApproval":"2021-01-19","patentExpiry":"Nov 26, 2032","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"carbocromen","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nesiritide","brandName":"nesiritide","genericName":"nesiritide","approvalYear":"2001","relationship":"same-class"},{"drugId":"vericiguat","brandName":"vericiguat","genericName":"vericiguat","approvalYear":"2021","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000167016","NDDF":"007146","UNII":"R0C9NIE5JJ","CHEBI":"CHEBI:135525","INN_ID":"1677","RXNORM":"2508","UMLSCUI":"C0008593","ChEMBL_ID":"CHEMBL2104512","KEGG_DRUG":"D07619","DRUGBANK_ID":"DB13279","PUBCHEM_CID":"12604","SECONDARY_CAS_RN":"655-35-6","MESH_DESCRIPTOR_UI":"D002866"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C01DX05","allCodes":["C01DX05"]},"biosimilarFilings":[],"recentPublications":[{"date":"1996 Feb 19","pmid":"8601429","title":"Antioxidants differentially affect nuclear factor kappa B-mediated nitric oxide synthase expression in vascular smooth muscle cells.","journal":"FEBS letters"},{"date":"1991 Feb","pmid":"1991345","title":"Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts.","journal":"Circulation research"},{"date":"1990 Apr-Jun","pmid":"2201083","title":"Drug test value by transcranial Doppler in the diagnosis of neurologic vascular diseases.","journal":"Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie"},{"date":"1988 May-Jun","pmid":"3285823","title":"Decreased coronary vascular reserve in Watanabe heritable hyperlipidemic rabbits.","journal":"Arteriosclerosis (Dallas, Tex.)"},{"date":"1985 Jul-Aug","pmid":"2410706","title":"Cardioprotective effects of carbocromen in awake and anesthetized dogs with amitriptyline poisoning.","journal":"Journal of cardiovascular pharmacology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Chromonar, also known as carbocromen, is a small molecule drug in the carbocromen class. Its exact target and mechanism of action are unknown, but it is believed to work by stabilizing cell membranes and preventing the release of certain chemicals. Chromonar's commercial status and approved indications are unclear, and it is not known whether it is patented or available as a generic medication. Further research is needed to fully understand its effects and potential uses. As a result, Chromonar is not widely recognized or used in clinical practice.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}