{"id":"carbenin","rwe":[{"pmid":"38432527","year":"2024","title":"Improved seizure liability detection by combining rat hippocampal brain slice electrophysiology with in vivo behavior observation following intracerebroventricular drug administration.","finding":"","journal":"Journal of pharmacological and toxicological methods","studyType":"Clinical Study"},{"pmid":"17880792","year":"2007","title":"[Clinical value and multiple risk factors analysis of sputum culture for fungus in neonates].","finding":"","journal":"Zhonghua er ke za zhi = Chinese journal of pediatrics","studyType":"Clinical Study"},{"pmid":"16161752","year":"2005","title":"[Surveillance of susceptibility of clinical isolates to panipenem between 2000 and 2003].","finding":"","journal":"The Japanese journal of antibiotics","studyType":"Clinical Study"},{"pmid":"15729484","year":"2005","title":"Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.","finding":"","journal":"Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy","studyType":"Clinical Study"},{"pmid":"12621735","year":"2002","title":"[Antibacterial activity of panipenem against clinical isolates in 2000 and 2001].","finding":"","journal":"The Japanese journal of antibiotics","studyType":"Clinical Study"}],"tags":[{"label":"carbenin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"panipenem-betamipron mixt","offLabel":[],"synonyms":["carbenin","Panipenem-betamipron mixt"],"timeline":[],"brandName":"Panipenem-Betamipron Mixt","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"carbenin","explanation":"Imagine your body's cells are like buildings, and the bacteria are like construction workers. Panipenem-Betamipron Mixt stops the construction workers from building new walls, which eventually causes the building to collapse and the bacteria to die.","oneSentence":"Panipenem-Betamipron Mixt works by inhibiting bacterial cell wall synthesis, ultimately leading to bacterial cell death.","technicalDetail":"Panipenem-Betamipron Mixt exerts its antibacterial effect by inhibiting the bacterial enzyme transpeptidase, which is essential for the cross-linking of peptidoglycan in the bacterial cell wall."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3891","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=carbenin","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:11:05.093107","biosimilars":[],"competitors":[],"genericName":"carbenin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"PUBCHEM_CID":"115235"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[{"date":"2024 Mar-Apr","pmid":"38432527","title":"Improved seizure liability detection by combining rat hippocampal brain slice electrophysiology with in vivo behavior observation following intracerebroventricular drug administration.","journal":"Journal of pharmacological and toxicological methods"},{"date":"2007 Jun","pmid":"17880792","title":"[Clinical value and multiple risk factors analysis of sputum culture for fungus in neonates].","journal":"Zhonghua er ke za zhi = Chinese journal of pediatrics"},{"date":"2005 Jun","pmid":"16161752","title":"[Surveillance of susceptibility of clinical isolates to panipenem between 2000 and 2003].","journal":"The Japanese journal of antibiotics"},{"date":"2005 Feb","pmid":"15729484","title":"Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.","journal":"Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy"},{"date":"2002 Dec","pmid":"12621735","title":"[Antibacterial activity of panipenem against clinical isolates in 2000 and 2001].","journal":"The Japanese journal of antibiotics"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Panipenem-Betamipron Mixt is a carbapenem antibiotic marketed by Daiichi Sankyo Co. of Japan, launched in 1993 under the brand name Carbenin.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}