{"id":"carbarsone","rwe":[{"pmid":"33484954","year":"2021","title":"Selective solid-phase extraction of four phenylarsonic compounds from feeds, edible chicken and pork with tailoring imprinted polymer.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"26617022","year":"2016","title":"Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring organoarsenic compounds in edible chicken and pork and feed.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"25608233","year":"2015","title":"Environmental concerns of roxarsone in broiler poultry feed and litter in Maryland, USA.","finding":"","journal":"Environmental science & technology","studyType":"Clinical Study"},{"pmid":"25461415","year":"2015","title":"Organoarsenicals in poultry litter: detection, fate, and toxicity.","finding":"","journal":"Environment international","studyType":"Clinical Study"},{"pmid":"24533282","year":"2012","title":"Current treatment options for Dientamoeba fragilis infections.","finding":"","journal":"International journal for parasitology. Drugs and drug resistance","studyType":"Clinical Study"}],"tags":[{"label":"carbarsone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Acute amebiasis","category":"indication"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"aminarson","offLabel":[],"synonyms":["carbarsone","amebarsene","amebarsone","aminarson","arsambide","carbarson","fenarsone","leucarsone","pentarsone","p-Ureidobenzenearsonic acid"],"timeline":[],"brandName":"Aminarson","ecosystem":[{"indication":"Acute amebiasis","otherDrugs":[{"name":"metronidazole","slug":"metronidazole","company":"Gd Searle Llc"},{"name":"paromomycin","slug":"paromomycin","company":""},{"name":"tinidazole","slug":"tinidazole","company":"Mission Pharma"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"carbarsone","explanation":"Imagine your body is a garden, and the parasite is a weed that's taking over. Aminarson is like a weed killer that stops the weed from growing and eventually kills it, allowing your body's natural defenses to take over and heal.","oneSentence":"Aminarson works by inhibiting the growth of the parasite Entamoeba histolytica, ultimately leading to its death.","technicalDetail":"Carbarsone is a sulfonamide antimicrobial agent that inhibits the synthesis of folic acid in the parasite, which is essential for its growth and survival."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Carbarsone","title":"Carbarsone","extract":"Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3065","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=carbarsone","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Carbarsone","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:09:58.848336","biosimilars":[],"competitors":[],"genericName":"carbarsone","indications":{"approved":[{"name":"Acute amebiasis","source":"DrugCentral","snomedId":39224005,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"002950","UNII":"8PK70TXE1T","CHEBI":"CHEBI:94806","INN_ID":"384","RXNORM":"20206","UMLSCUI":"C0054654","ChEMBL_ID":"CHEMBL1331366","DRUGBANK_ID":"DB11382","PUBCHEM_CID":"8480","MESH_SUPPLEMENTAL_RECORD_UI":"C033007"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":61,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2021 Jun 15","pmid":"33484954","title":"Selective solid-phase extraction of four phenylarsonic compounds from feeds, edible chicken and pork with tailoring imprinted polymer.","journal":"Food chemistry"},{"date":"2016 Apr 15","pmid":"26617022","title":"Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring organoarsenic compounds in edible chicken and pork and feed.","journal":"Food chemistry"},{"date":"2015 Feb 17","pmid":"25608233","title":"Environmental concerns of roxarsone in broiler poultry feed and litter in Maryland, USA.","journal":"Environmental science & technology"},{"date":"2015 Feb","pmid":"25461415","title":"Organoarsenicals in poultry litter: detection, fate, and toxicity.","journal":"Environment international"},{"date":"2012 Dec","pmid":"24533282","title":"Current treatment options for Dientamoeba fragilis infections.","journal":"International journal for parasitology. Drugs and drug resistance"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Aminarson, also known as carbarsone, is a small molecule drug in the carbarsone class. It is used to treat acute amebiasis, a condition caused by the parasite Entamoeba histolytica. The commercial status of Aminarson is unclear, but it is likely to be a generic or off-patent medication. Aminarson's mechanism of action involves inhibiting the growth of the parasite, ultimately leading to its death. Further information on its development, approval, and safety considerations is needed.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}