{"id":"caralluma-fimbriata","safety":{"commonSideEffects":[{"rate":"null","effect":"Nausea"},{"rate":"null","effect":"Headache"},{"rate":"null","effect":"Dizziness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The exact mechanism of action of caralluma fimbriata is not fully understood, but it is believed to work by suppressing appetite and reducing food intake. This is thought to be achieved through the inhibition of citrate lyase, an enzyme involved in fat synthesis. As a result, caralluma fimbriata may help with weight loss and improve overall metabolic health.","oneSentence":"Caralluma fimbriata is thought to suppress appetite and reduce food intake by inhibiting the activity of citrate lyase, an enzyme involved in fat synthesis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:49:04.541Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Weight loss"}]},"trialDetails":[{"nctId":"NCT05232266","phase":"PHASE2, PHASE3","title":"The Effectiveness of a Caralluma Fimbriata Extract on Stress, Sleep and Neurotransmitters","status":"COMPLETED","sponsor":"RDC Clinical Pty Ltd","startDate":"2022-02-10","conditions":"Stress, Sleep","enrollment":129}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":33,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["C.fimbriata"],"phase":"phase_2","status":"active","brandName":"Caralluma Fimbriata","genericName":"Caralluma Fimbriata","companyName":"RDC Clinical Pty Ltd","companyId":"rdc-clinical-pty-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Caralluma fimbriata is thought to suppress appetite and reduce food intake by inhibiting the activity of citrate lyase, an enzyme involved in fat synthesis. Used for Weight loss.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}