{"id":"calusterone","rwe":[],"tags":[{"label":"calusterone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"methosarb","offLabel":[],"synonyms":["calusterone","methosarb"],"timeline":[],"brandName":"Methosarb","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"calusterone","explanation":"Think of it like a key that fits into a lock, but instead of unlocking a door, it blocks a specific pathway in the body that cells use to communicate with each other. This can help slow down or stop the growth of certain cells, but it's a complex process and more research is needed to fully understand how it works. By blocking this pathway, methosarb may be able to treat certain diseases or conditions, but it's still a relatively unknown drug.","oneSentence":"Methosarb works by inhibiting certain cellular processes, although the exact mechanism is unknown.","technicalDetail":"Calusterone is a small molecule that binds to and inhibits the activity of certain proteins involved in cellular signaling pathways, although the specific molecular targets and mechanisms of action are currently unknown."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Calusterone","title":"Calusterone","extract":"Calusterone, also known as 7β,17α-dimethyltestosterone, is an orally active anabolic-androgenic steroid (AAS) that is used as an antineoplastic agent. It is a 17α-alkylated AAS similar in structure to bolasterone."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/468","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CALUSTERONE","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Calusterone","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:08:15.961241","biosimilars":[],"competitors":[],"genericName":"calusterone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"002666","UNII":"0678G6Q58A","CHEBI":"CHEBI:135356","INN_ID":"2873","UMLSCUI":"C0006790","ChEMBL_ID":"CHEMBL455706","KEGG_DRUG":"D03338","DRUGBANK_ID":"DB01564","PUBCHEM_CID":"28204","SNOMEDCT_US":"59489005","MESH_SUPPLEMENTAL_RECORD_UI":"C073055"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":30,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Methosarb is a small molecule with the synonyms CALUSTERONA, CALUSTERONE, CALUSTERONE, DIMETHYLTESTOSTERONE, and NSC-88536.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}