{"id":"calgel","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or sensitivity"},{"rate":null,"effect":"Allergic reaction to anesthetic agents"}]},"_chembl":{"chemblId":"CHEMBL79","moleculeType":"Small molecule","molecularWeight":"234.34"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Calgel® typically contains local anesthetic agents (such as benzocaine or lidocaine) combined with anti-inflammatory components to numb oral tissues and reduce inflammation. The formulation is applied directly to affected oral areas to provide symptomatic relief of pain associated with teething, mouth ulcers, or other oral conditions.","oneSentence":"Calgel® is a topical oral gel formulation designed to provide local anesthetic and anti-inflammatory relief for oral pain and discomfort.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:04:41.722Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Oral pain relief (teething, mouth ulcers, oral irritation)"}]},"trialDetails":[{"nctId":"NCT02931357","phase":"PHASE3","title":"Study of a New Medical Device in Gel Formulation Versus Calgel® for the Topical Treatment of Teething in Infants","status":"COMPLETED","sponsor":"Ricerfarma S.r.l","startDate":"2013-09","conditions":"Pain Teeth","enrollment":54}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Lidocaine 0.33% and Cetylpyridinium Chloride 0.10%"],"phase":"phase_3","status":"active","brandName":"Calgel®","genericName":"Calgel®","companyName":"Ricerfarma S.r.l","companyId":"ricerfarma-s-r-l","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Calgel® is a topical oral gel formulation designed to provide local anesthetic and anti-inflammatory relief for oral pain and discomfort. Used for Oral pain relief (teething, mouth ulcers, oral irritation).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}