{"id":"calcium-lactate-gluconate","rwe":[{"pmid":"39418945","year":"2025","title":"Formation of furan and furan derivatives in baby food products.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"36808216","year":"2023","title":"Effect of soluble corn fibre and calcium supplementation on bone mineral content and bone mineral density in preadolescent Malaysian children-a double-blind randomised controlled trial (PREBONE-Kids Study).","finding":"","journal":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA","studyType":"Clinical Study"},{"pmid":"34822650","year":"2021","title":"Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress.","finding":"","journal":"Veterinary sciences","studyType":"Clinical Study"},{"pmid":"32864210","year":"2020","title":"Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease.","finding":"","journal":"PeerJ","studyType":"Clinical Study"},{"pmid":"32619118","year":"2020","title":"Formulation development of paracetamol instant jelly for pediatric use.","finding":"","journal":"Drug development and industrial pharmacy","studyType":"Clinical Study"}],"tags":[{"label":"calcium lactate gluconate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A12AA06","category":"atc"},{"label":"Active","category":"status"},{"label":"Hypocalcemia","category":"indication"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"calcium gluconolactate","offLabel":[],"synonyms":["calcium lactate gluconate","calcium gluconolactate"],"timeline":[],"brandName":"Calcium Gluconolactate","ecosystem":[{"indication":"Hypocalcemia","otherDrugs":[{"name":"calcifediol","slug":"calcifediol","company":""},{"name":"calcitriol","slug":"calcitriol","company":"Validus Pharms"},{"name":"calcium acetate","slug":"calcium-acetate","company":"B Braun"},{"name":"calcium carbonate","slug":"calcium-carbonate","company":"Mcneil Cons"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"calcium lactate gluconate","explanation":"Imagine your body's calcium levels are like a bank account. When you have hypocalcemia, your calcium account is low. Calcium Gluconolactate helps to deposit more calcium into your account, bringing your levels back up to normal.","oneSentence":"Calcium Gluconolactate works by replenishing calcium stores in the body.","technicalDetail":"Calcium Gluconolactate is a calcium salt that is absorbed into the bloodstream, where it can be used to replenish calcium stores in the body, primarily in the bones, muscles, and nervous system."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Calcium_lactate_gluconate","title":"Calcium lactate gluconate","extract":"Calcium lactate gluconate, also known as GLOCAL, is a soluble salt of calcium, lactic acid and gluconic acid used in effervescent calcium tablets. Its chemical formula is Ca5(C3H5O3)6·(C6H11O7)4·2H2O. It was first developed by Sandoz, Switzerland. Calcium lactate gluconate is used in the functional and fortified food industry due to its good solubility and neutral taste. In addition, it is used in various spherification techniques in molecular gastronomy. It can also be used to help neutralize HF (hydrofluoric acid) poisoning."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4843","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=calcium%20lactate%20gluconate","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=calcium lactate gluconate","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Calcium_lactate_gluconate","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:09:19.128334","biosimilars":[],"competitors":[{"drugName":"calcium phosphate","drugSlug":"calcium-phosphate","fdaApproval":"","relationship":"same-class"},{"drugName":"calcium gluconate","drugSlug":"calcium-gluconate","fdaApproval":"","patentExpiry":"Jul 25, 2037","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"calcium carbonate","drugSlug":"calcium-carbonate","fdaApproval":"2000-10-16","relationship":"same-class"},{"drugName":"calcium chloride","drugSlug":"calcium-chloride","fdaApproval":"1971-03-22","genericCount":7,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"calcium glycerylphosphate","drugSlug":"calcium-glycerylphosphate","fdaApproval":"","relationship":"same-class"},{"drugName":"calcium glucoheptonate","drugSlug":"calcium-glucoheptonate","fdaApproval":"1972-12-04","relationship":"same-class"},{"drugName":"calcium citrate","drugSlug":"calcium-citrate","fdaApproval":"","relationship":"same-class"}],"genericName":"calcium lactate gluconate","indications":{"approved":[{"name":"Hypocalcemia","source":"DrugCentral","snomedId":5291005,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"calcium-phosphate","brandName":"calcium phosphate","genericName":"calcium phosphate","approvalYear":"","relationship":"same-class"},{"drugId":"calcium-gluconate","brandName":"calcium gluconate","genericName":"calcium gluconate","approvalYear":"","relationship":"same-class"},{"drugId":"calcium-carbonate","brandName":"calcium carbonate","genericName":"calcium carbonate","approvalYear":"2000","relationship":"same-class"},{"drugId":"calcium-chloride","brandName":"calcium chloride","genericName":"calcium chloride","approvalYear":"1971","relationship":"same-class"},{"drugId":"calcium-glycerylphosphate","brandName":"calcium glycerylphosphate","genericName":"calcium glycerylphosphate","approvalYear":"","relationship":"same-class"},{"drugId":"calcium-glucoheptonate","brandName":"calcium glucoheptonate","genericName":"calcium glucoheptonate","approvalYear":"1972","relationship":"same-class"},{"drugId":"calcium-citrate","brandName":"calcium citrate","genericName":"calcium citrate","approvalYear":"","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT04102371","phase":"PHASE3","title":"Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis","status":"COMPLETED","sponsor":"Children's Hospital of Philadelphia","startDate":"2020-08-25","conditions":["Shock","Septic"],"enrollment":9041,"completionDate":"2026-01-31"},{"nctId":"NCT04966507","phase":"PHASE2","title":"Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention","status":"COMPLETED","sponsor":"University of California, Los Angeles","startDate":"2022-02-17","conditions":["Gonorrhea"],"enrollment":89,"completionDate":"2025-12-12"},{"nctId":"NCT05860062","phase":"NA","title":"Vitamin D Supplementation in Episodic and Chronic Tension-type Headache","status":"UNKNOWN","sponsor":"Hospital de Especialidades, Centro Medico Nacional \"La Raza\", Instituto Mexicano del Seguro Social","startDate":"2023-04-18","conditions":["Chronic Tension-Type Headache"],"enrollment":20,"completionDate":"2023-12-20"},{"nctId":"NCT05743751","phase":"NA","title":"Normothermic Machine Perfusion (NMP) Versus Hypothermic Machine Perfusion (HMP) in Human Kidney Transplantation","status":"UNKNOWN","sponsor":"Zhang Tianyu","startDate":"2023-03-03","conditions":["Kidney Transplantation"],"enrollment":60,"completionDate":"2025-09-03"},{"nctId":"NCT03054922","phase":"PHASE3","title":"Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables","status":"COMPLETED","sponsor":"Nationwide Children's Hospital","startDate":"2017-02-23","conditions":["Anesthesia"],"enrollment":59,"completionDate":"2018-09-30"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005559","UNII":"472LWJ3Y9N","UMLSCUI":"C0771535","ChEMBL_ID":"CHEMBL3707385","DRUGBANK_ID":"DB13365","PUBCHEM_CID":"92237","SNOMEDCT_US":"421198002"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":27,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"A12AA06","allCodes":["A12AA06"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025 Feb 1","pmid":"39418945","title":"Formation of furan and furan derivatives in baby food products.","journal":"Food chemistry"},{"date":"2023 Apr","pmid":"36808216","title":"Effect of soluble corn fibre and calcium supplementation on bone mineral content and bone mineral density in preadolescent Malaysian children-a double-blind randomised controlled trial (PREBONE-Kids Study).","journal":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"date":"2021 Nov 15","pmid":"34822650","title":"Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress.","journal":"Veterinary sciences"},{"date":"2020","pmid":"32864210","title":"Efficacy of a new dietary supplement in dogs with advanced chronic kidney disease.","journal":"PeerJ"},{"date":"2020 Aug","pmid":"32619118","title":"Formulation development of paracetamol instant jelly for pediatric use.","journal":"Drug development and industrial pharmacy"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Calcium gluconolactate is a small molecule with the synonyms calcium gluconolactate, calcium lactate gluconate, calcium lactogluconate, and calcium (as lactate gluconate). It is used in the functional and fortified food industry due to its good solubility and neutral taste.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}