{"id":"calcium-carbimide","rwe":[],"tags":[{"label":"calcium carbimide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N07BB02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cyanamid","offLabel":[],"synonyms":["calcium carbimide","calcium cyanamide","cyanamid"],"timeline":[],"brandName":"Cyanamid","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"calcium carbimide","explanation":"Imagine your body's cells are like factories that use enzymes to get things done. Calcium carbimide is like a tool that blocks some of these enzymes, which can help slow down or stop certain processes in the body. This can be useful in treating certain conditions, but more research is needed to understand how it works and its potential side effects.","oneSentence":"Calcium carbimide works by inhibiting the activity of certain enzymes involved in cellular processes.","technicalDetail":"Calcium carbimide is a calcium salt of carbimide, a compound that inhibits the activity of certain enzymes, including those involved in cellular respiration and metabolism."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/American_Cyanamid","title":"American Cyanamid","extract":"American Cyanamid was an American manufacturing conglomerate. Originally begun as a fertilizer manufacturer, the company added many additional lines of business before merging with American Home Products in 1994. The combined company sold off most of its divisions, adopted the name of its remaining Wyeth division, and was bought by Pfizer in 2009.","wiki_history":"== History ==\nthumb|American Cyanamid Company facility in [[Linden, New Jersey]]\n\nAmerican Cyanamid was founded by engineers Frank S. Washburn and Charles H. Baker in New York City in 1907, to capitalize on a German patent that they had licensed for the manufacture of nitrogen products for fertilizer. The company's name is derived from the chemical calcium cyanamide, the fertilizer they would manufacture. They soon set up headquarters in Nashville, investing a million dollars in several corporations underpinning the manufacturing operation to be set up in nearby Muscle Shoals, Alabama. These planned operations included an electric power generating company, a utility company to distribute the electricity powering the chemical plant, and the Cyanamid manufacturing plant. Plants were also planned for Niagara Falls, Ontario and Georgia, and by 1908, the company had incorporated in Maine. The Canadian plant was the first in operation in 1910, followed by the Alabama plant. Washburn was President and located in Nashville, while Baker served as Vice President and remained in New York. \n\nDespite these early establishments, manufacturing was suspended when the company was denied the construction of a dam for the hydroelectric generation station. Instead, United States offices of the company imported product from its Canadian plant to compensate for fewer resources. In 1915, the company abandoned its Nashville headquarters and relocated to New York City. At the same time, it was trying to raise political support, both through grass-roots and lobbying, to implement the Alabama power generation plan and compete in the growing market. During World War I, the company shifted its nitrogen production from fertilizer to explosives. With offers of free use of patents and processes, along with personnel and equipment, it enticed the federal government to approve and pay for its original plans for the Alabama plant, with some modifications, to contribute to the war effort. A separate c"},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4432","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CALCIUM CARBIMIDE","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/American_Cyanamid","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:08:38.520320","biosimilars":[],"competitors":[{"drugName":"disulfiram","drugSlug":"disulfiram","fdaApproval":"1951-08-28","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"acamprosate","drugSlug":"acamprosate","fdaApproval":"2004-07-29","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"naltrexone","drugSlug":"naltrexone","fdaApproval":"1984-11-20","patentExpiry":"Oct 15, 2029","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"nalmefene","drugSlug":"nalmefene","fdaApproval":"1995-04-17","patentExpiry":"Nov 5, 2039","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"calcium carbimide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"disulfiram","brandName":"disulfiram","genericName":"disulfiram","approvalYear":"1951","relationship":"same-class"},{"drugId":"acamprosate","brandName":"acamprosate","genericName":"acamprosate","approvalYear":"2004","relationship":"same-class"},{"drugId":"naltrexone","brandName":"naltrexone","genericName":"naltrexone","approvalYear":"1984","relationship":"same-class"},{"drugId":"nalmefene","brandName":"nalmefene","genericName":"nalmefene","approvalYear":"1995","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"003942","UNII":"ZLR270912W","CHEBI":"CHEBI:64301","INN_ID":"880","RXNORM":"1902","UMLSCUI":"C1611088","ChEMBL_ID":"CHEMBL3301667","KEGG_DRUG":"D03288","DRUGBANK_ID":"DB09116","PUBCHEM_CID":"56955933","SNOMEDCT_US":"41793006","MESH_DESCRIPTOR_UI":"D003484"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":83,"therapeuticAreas":["Metabolic"],"atcClassification":{"source":"DrugCentral","atcCode":"N07BB02","allCodes":["N07BB02"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cyanamid is a small molecule compound with the synonyms Calcium Carbimide, Calcium Carbimide, Calcium Cyanamide, and others. It is a calcium salt of cyanamide.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}