{"id":"cacodylic-acid","rwe":[{"pmid":"41707867","year":"2026","title":"Impact of rice residue decomposition on the diffusion of perfluoroalkyl substances in drainage and waterlogged paddy fields.","finding":"","journal":"Environmental pollution (Barking, Essex : 1987)","studyType":"Clinical Study"},{"pmid":"41226158","year":"2025","title":"Iron-Based Metal-Organic Frameworks for the Removal of Different Organic and Inorganic Arsenic Species from Water: Kinetic and Adsorption Studies.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41160850","year":"2025","title":"Cytomorphological characteristics of the Nasopharyngeal zone mucosa in children with Covid-19.","finding":"","journal":"Wiadomosci lekarskie (Warsaw, Poland : 1960)","studyType":"Clinical Study"},{"pmid":"40831218","year":"2025","title":"Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure.","finding":"","journal":"Advanced science (Weinheim, Baden-Wurttemberg, Germany)","studyType":"Clinical Study"},{"pmid":"39554609","year":"2024","title":"Polygenic anti-cancer activity of Indigofera macrophylla in prostate cancer induced animal model.","finding":"","journal":"Toxicology reports","studyType":"Clinical Study"}],"tags":[{"label":"cacodylic acid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Herbicides","category":"pharmacology"},{"label":"Pesticides","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"dimethylarsenic acid","offLabel":[],"synonyms":["cacodylic acid","dimethylarsenic acid","dimethylarsinic acid","hydroxydimethylarsine oxide"],"timeline":[],"brandName":"Dimethylarsenic Acid","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cacodylic acid","explanation":"Imagine cacodylic acid as a puzzle piece that fits into a specific spot in a cell, but instead of helping the cell work properly, it causes problems and disrupts the cell's normal function. This can lead to a range of effects, but the exact way it works is still not well understood. More research is needed to figure out how it interacts with cells and tissues.","oneSentence":"Cacodylic acid works by disrupting cellular processes, although the exact mechanism is unclear.","technicalDetail":"Cacodylic acid is a small molecule that likely interacts with cellular targets, potentially disrupting arsenic metabolism or other cellular processes, although the precise mechanism of action remains unknown."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Cacodylic_acid","title":"Cacodylic acid","extract":"Cacodylic acid is an organoarsenic compound with the formula (CH3)2AsO2H. With the formula R2As(O)OH, it is the simplest of the arsinic acids. It is a colorless solid that is soluble in water.","wiki_history":"== History ==\nIn the 18th century it was found that combining arsenic trioxide () and four equivalents of potassium acetate () gives a product called \"Cadet's fuming liquid\" which contains cacodyl oxide,  and cacodyl, .\n\nEarly research into \"cacodyls\" was reported by Robert Bunsen at the University of Marburg. Bunsen said of the compounds,\n\n<blockquote>\"The smell of this body produces instantaneous tingling of the hands and feet, and even giddiness and insensibility... It is remarkable that when one is exposed to the smell of these compounds the tongue becomes covered with a black coating, even when no further evil effects are noticeable\".</blockquote>\n\nHis work in this field led to an increased understanding of the methyl group.\n\nCacodyl oxide, , is often considered the first organometallic compound to be prepared synthetically.\n\nCacodylic acid and its salts were incorporated into herbicides by a large variety of manufacturers under numerous brand names. APC Holdings Corp. sold cacodylic acid and its salts under the Phytar brand name. The variety Phytar 560G, a mixture of cacodylic acid and sodium cacodylate, was used during the Vietnam War as a defoliant under the name \"Agent Blue\"."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3058","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cacodylic acid","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Cacodylic_acid","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:06:23.259930","biosimilars":[],"competitors":[],"genericName":"cacodylic acid","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"AJ2HL7EU8K","CHEBI":"CHEBI:48765","UMLSCUI":"C0006628","ChEMBL_ID":"CHEMBL1231644","DRUGBANK_ID":"DB02994","PDB_CHEM_ID":" CAD","PUBCHEM_CID":"2513","MESH_DESCRIPTOR_UI":"D002101"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":91,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Apr 15","pmid":"41707867","title":"Impact of rice residue decomposition on the diffusion of perfluoroalkyl substances in drainage and waterlogged paddy fields.","journal":"Environmental pollution (Barking, Essex : 1987)"},{"date":"2025 Oct 27","pmid":"41226158","title":"Iron-Based Metal-Organic Frameworks for the Removal of Different Organic and Inorganic Arsenic Species from Water: Kinetic and Adsorption Studies.","journal":"Molecules (Basel, Switzerland)"},{"date":"2025","pmid":"41160850","title":"Cytomorphological characteristics of the Nasopharyngeal zone mucosa in children with Covid-19.","journal":"Wiadomosci lekarskie (Warsaw, Poland : 1960)"},{"date":"2025 Nov","pmid":"40831218","title":"Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure.","journal":"Advanced science (Weinheim, Baden-Wurttemberg, Germany)"},{"date":"2024 Dec","pmid":"39554609","title":"Polygenic anti-cancer activity of Indigofera macrophylla in prostate cancer induced animal model.","journal":"Toxicology reports"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Dimethylarsenic Acid, also known as cacodylic acid, is a small molecule drug of the cacodylic acid class. Its mechanism of action and target are unknown, and it is not FDA-approved for any indications. As a result, there is limited information available on its commercial status, safety considerations, or pharmacokinetic properties. Further research is needed to understand the potential benefits and risks of this compound. Due to its lack of FDA approval, it is not available as a generic or patented medication.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}