{"id":"bxt-51072","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased risk of diabetic ketoacidosis"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting the SGLT2 receptor, BXT-51072 reduces glucose reabsorption in the kidneys, thereby lowering blood glucose levels. This mechanism is similar to other SGLT2 inhibitors, which have been shown to be effective in treating type 2 diabetes. BXT-51072 is being investigated for its potential to improve glycemic control in patients with type 2 diabetes.","oneSentence":"BXT-51072 is a small molecule inhibitor of the SGLT2 receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:59:09.704Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Type 2 diabetes"}]},"trialDetails":[{"nctId":"NCT00320502","phase":"PHASE2","title":"A Phase 2 Study to Determine the Effects of BXT-51072 in Diabetic Patients Undergoing Angioplasty (PCI)","status":"COMPLETED","sponsor":"Synvista Therapeutics, Inc","startDate":"2006-05","conditions":"Acute Coronary Syndrome, Type 2 Diabetes","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":8,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"BXT-51072","genericName":"BXT-51072","companyName":"Synvista Therapeutics, Inc","companyId":"synvista-therapeutics-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BXT-51072 is a small molecule inhibitor of the SGLT2 receptor. Used for Type 2 diabetes.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}