{"id":"buzepide-metiodide","rwe":[{"pmid":"2672998","year":"1989","title":"[Effect of a buzepide metiodide-haloperidol combination in treating functional intestinal disorders. Randomized double-blind controlled versus placebo study].","finding":"","journal":"Annales de gastroenterologie et d'hepatologie","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"metazepium iodide","offLabel":[],"synonyms":["buzepide metiodide","metazepium iodide","diphexamide iodomethylate","difexamide methiodide"],"timeline":[],"brandName":"Metazepium Iodide","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your brain is a complex network of roads and intersections. Metazepine iodide is like a traffic controller that tries to regulate the flow of information between different parts of the brain. However, since its exact mechanism is unknown, it's like trying to navigate a road system without a map.","oneSentence":"Metazepine iodide is thought to work by interacting with specific biological pathways, but the exact mechanism is unknown.","technicalDetail":"As a small molecule, metazepine iodide likely works by binding to specific receptors or enzymes in the brain, altering the normal functioning of neurotransmitter systems. However, without more information on its target and drug class, it's difficult to provide a detailed explanation of its pharmacology."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/459","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BUZEPIDE METIODIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:07:07.316847","biosimilars":[],"competitors":[],"genericName":"buzepide metiodide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"004307","UNII":"5A9SS67K16","CHEBI":"CHEBI:135429","INN_ID":"1590","RXNORM":"19943","UMLSCUI":"C0054323","ChEMBL_ID":"CHEMBL2106132","PUBCHEM_CID":"27206","MESH_SUPPLEMENTAL_RECORD_UI":"C021334"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1989 May","pmid":"2672998","title":"[Effect of a buzepide metiodide-haloperidol combination in treating functional intestinal disorders. Randomized double-blind controlled versus placebo study].","journal":"Annales de gastroenterologie et d'hepatologie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Metazepine iodide is a small molecule with synonyms including Buzepide methiodide, Diphehexamide methiodide, and F.I. 6146.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}