{"id":"butoxycaine","rwe":[{"pmid":"32019308","year":"2020","title":"Scalable and Phosphine-Free Conversion of Alcohols to Carbon-Heteroatom Bonds through the Blue Light-Promoted Iodination Reaction.","finding":"","journal":"The Journal of organic chemistry","studyType":"Clinical Study"},{"pmid":"24808991","year":"2014","title":"Room temperature, metal-free arylation of aliphatic alcohols.","finding":"","journal":"ChemistryOpen","studyType":"Clinical Study"}],"tags":[{"label":"butoxycaine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"_fixedAt":"2026-03-30T16:40:24.434613","allNames":["butoxycaine hydrochloride","butoxycaine","butoxycaine HCl"],"offLabel":[],"synonyms":["butoxycaine hydrochloride","butoxycaine","butoxycaine HCl"],"timeline":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"butoxycaine","explanation":"Imagine your nerves are like electrical wires that send signals to your brain. Butoxycaine is like a switch that turns off the flow of electricity in these wires, preventing pain signals from reaching your brain. This helps to numb the area and relieve pain.","oneSentence":"Butoxycaine works by blocking sodium channels in nerve cells to prevent pain signals from being transmitted.","technicalDetail":"Butoxycaine exerts its analgesic effect by selectively blocking voltage-gated sodium channels, which are responsible for the initial depolarization of nerve cells and the transmission of pain signals."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3055","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=butoxycaine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:09:51.668995","biosimilars":[],"competitors":[],"genericName":"butoxycaine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"_fixedFields":["pubmed(2)"],"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007075","UNII":"89M880K35B","RXNORM":"236881","UMLSCUI":"C0772206","PUBCHEM_CID":"16882","SECONDARY_CAS_RN":"2350-32-5"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[{"date":"2020 Mar 6","pmid":"32019308","title":"Scalable and Phosphine-Free Conversion of Alcohols to Carbon-Heteroatom Bonds through the Blue Light-Promoted Iodination Reaction.","journal":"The Journal of organic chemistry"},{"date":"2014 Apr","pmid":"24808991","title":"Room temperature, metal-free arylation of aliphatic alcohols.","journal":"ChemistryOpen"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"butoxycaine","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Butoxycaine is a small molecule drug in the butoxycaine class, but its original developer and current owner are unknown. Its target and approved indications are also not specified. The commercial status of butoxycaine is unclear, with unknown patent status and generic manufacturers. Further information on its pharmacokinetics, such as half-life and bioavailability, is also lacking. As a result, key safety considerations and clinical use cannot be accurately assessed.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}