{"id":"butanilicaine","rwe":[],"tags":[{"label":"butanilicaine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N01BB05","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"hostacaine","offLabel":[],"synonyms":["butanilicaine phosphate","butanilicaine monohydrochloride","butanilicaine hydrochloride","hostacaine","butanilicaine"],"timeline":[],"brandName":"Hostacaine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"butanilicaine","explanation":"Imagine your body has a 'pain switch' that can be flipped on or off. Hostacaine is a key that can turn this switch off, reducing the sensation of pain. This is achieved by blocking the action of certain chemicals that transmit pain signals to the brain.","oneSentence":"Hostacaine works by blocking certain pain pathways in the body.","technicalDetail":"Butanilicaine is a local anesthetic that acts by inhibiting the voltage-gated sodium channels, which are responsible for the initiation and transmission of nerve impulses, thereby blocking the pain signal."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3691","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BUTANILICAINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:06:18.133822","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:48:48.535918+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"bupivacaine","drugSlug":"bupivacaine","fdaApproval":"1972-10-03","patentExpiry":"Mar 17, 2042","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"lidocaine","drugSlug":"lidocaine","fdaApproval":"1948-11-19","patentExpiry":"May 10, 2031","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"mepivacaine","drugSlug":"mepivacaine","fdaApproval":"1960-01-06","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"prilocaine","drugSlug":"prilocaine","fdaApproval":"1965-11-18","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"cinchocaine","drugSlug":"cinchocaine","fdaApproval":"","relationship":"same-class"},{"drugName":"etidocaine","drugSlug":"etidocaine","fdaApproval":"1976-08-30","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"articaine","drugSlug":"articaine","fdaApproval":"2000-04-03","patentExpiry":"Mar 27, 2039","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"ropivacaine","drugSlug":"ropivacaine","fdaApproval":"1996-09-24","patentExpiry":"Nov 28, 2026","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"levobupivacaine","drugSlug":"levobupivacaine","fdaApproval":"1999-08-05","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"meloxicam","drugSlug":"meloxicam","fdaApproval":"2000-04-13","patentExpiry":"May 26, 2030","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"butanilicaine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"bupivacaine","brandName":"bupivacaine","genericName":"bupivacaine","approvalYear":"1972","relationship":"same-class"},{"drugId":"lidocaine","brandName":"lidocaine","genericName":"lidocaine","approvalYear":"1948","relationship":"same-class"},{"drugId":"mepivacaine","brandName":"mepivacaine","genericName":"mepivacaine","approvalYear":"1960","relationship":"same-class"},{"drugId":"prilocaine","brandName":"prilocaine","genericName":"prilocaine","approvalYear":"1965","relationship":"same-class"},{"drugId":"cinchocaine","brandName":"cinchocaine","genericName":"cinchocaine","approvalYear":"","relationship":"same-class"},{"drugId":"etidocaine","brandName":"etidocaine","genericName":"etidocaine","approvalYear":"1976","relationship":"same-class"},{"drugId":"articaine","brandName":"articaine","genericName":"articaine","approvalYear":"2000","relationship":"same-class"},{"drugId":"ropivacaine","brandName":"ropivacaine","genericName":"ropivacaine","approvalYear":"1996","relationship":"same-class"},{"drugId":"levobupivacaine","brandName":"levobupivacaine","genericName":"levobupivacaine","approvalYear":"1999","relationship":"same-class"},{"drugId":"meloxicam","brandName":"meloxicam","genericName":"meloxicam","approvalYear":"2000","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"7X3WV51F4N","CHEBI":"CHEBI:55518","INN_ID":"2115","UMLSCUI":"C0054241","ChEMBL_ID":"CHEMBL2104238","KEGG_DRUG":"D07284","DRUGBANK_ID":"DB13328","PUBCHEM_CID":"22379","SECONDARY_CAS_RN":"2081-65-4","MESH_SUPPLEMENTAL_RECORD_UI":"C008337"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":11,"therapeuticAreas":["Pain"],"atcClassification":{"source":"DrugCentral","atcCode":"N01BB05","allCodes":["N01BB05"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Hostacaine (BUTANILICAINE) is a small molecule butanilicaine drug with unknown target and commercial status. Its mechanism of action is not well-documented, and it is not approved by the FDA for any indications. As a result, there is limited information available on its pharmacokinetics, safety, and efficacy. Further research is needed to understand the properties and potential uses of Hostacaine. Its current status as a developmental compound makes it difficult to assess its clinical utility.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:48:48.535918+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}