{"id":"buscopan-composto-association","safety":{"commonSideEffects":[{"rate":null,"effect":"Dry mouth"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Tachycardia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Hyoscine butylbromide works as a muscarinic receptor antagonist that reduces smooth muscle contractions in the gastrointestinal tract, thereby alleviating spasms and cramping pain. Paracetamol provides additional analgesic and antipyretic effects. This combination addresses both the mechanical pain of GI spasms and general pain/fever symptoms.","oneSentence":"Buscopan Composto combines hyoscine butylbromide (an anticholinergic agent) with paracetamol to relieve abdominal pain and cramping while reducing fever.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:55:27.407Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Abdominal pain and cramping associated with gastrointestinal spasms"},{"name":"Symptomatic relief of functional gastrointestinal disorders"}]},"trialDetails":[{"nctId":"NCT05640232","phase":"PHASE3","title":"Efficacy and Safety of CDE100 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea","status":"RECRUITING","sponsor":"EMS","startDate":"2025-06-11","conditions":"Primary Dysmenorrhea","enrollment":238}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Buscopan® Composto association","genericName":"Buscopan® Composto association","companyName":"EMS","companyId":"ems","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Buscopan Composto combines hyoscine butylbromide (an anticholinergic agent) with paracetamol to relieve abdominal pain and cramping while reducing fever. Used for Abdominal pain and cramping associated with gastrointestinal spasms, Symptomatic relief of functional gastrointestinal disorders.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}