{"id":"bupivacaine-injection","safety":{"commonSideEffects":[{"rate":null,"effect":"Nervousness or anxiety"},{"rate":null,"effect":"Dizziness or lightheadedness"},{"rate":null,"effect":"Tinnitus"},{"rate":null,"effect":"Tremor"},{"rate":null,"effect":"Hypotension"},{"rate":null,"effect":"Bradycardia"},{"rate":"<1","effect":"Allergic reactions (rare with amides)"}]},"_chembl":null,"_dailymed":{"setId":"06c15208-c600-7173-e063-6394a90a2f94","title":"BUPIVACAINE HYDROCHLORIDE INJECTION, SOLUTION INJECTION, SOLUTION [HF ACQUISITION CO LLC, DBA HEALTHFIRST]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bupivacaine is a long-acting amide local anesthetic that reversibly inhibits sodium influx into nerve fibers, stabilizing the neuronal membrane and raising the threshold for electrical excitability. This action prevents depolarization and propagation of action potentials, resulting in loss of sensation in the injected area. 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