{"id":"bupivacaine-fentanyl-morphine-elective-group","safety":{"commonSideEffects":[{"rate":null,"effect":"Respiratory depression"},{"rate":null,"effect":"Hypotension"},{"rate":null,"effect":"Nausea and vomiting"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Pruritus"},{"rate":null,"effect":"Local anesthetic toxicity (with bupivacaine)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bupivacaine blocks sodium channels in nerve fibers to provide local anesthesia at the injection site. Fentanyl and morphine are opioid agonists that bind to mu-opioid receptors in the central and peripheral nervous system to provide systemic analgesia and reduce pain perception. The combination is used perioperatively to manage pain during elective surgical procedures.","oneSentence":"This is a combination of three analgesic agents—bupivacaine (local anesthetic), fentanyl (opioid), and morphine (opioid)—that work together to provide local anesthesia and systemic pain relief for elective surgical procedures.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:29:08.922Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Perioperative pain management in elective surgical procedures"}]},"trialDetails":[{"nctId":"NCT03673280","phase":"NA","title":"Quadratus Lumborum in Cesarean Section Trial","status":"COMPLETED","sponsor":"University of Sao Paulo General Hospital","startDate":"2018-10-02","conditions":"Postoperative Analgesia","enrollment":61},{"nctId":"NCT05696678","phase":"NA","title":"Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery","status":"WITHDRAWN","sponsor":"Ciusss de L'Est de l'Île de Montréal","startDate":"2023-02","conditions":"Quality of Recovery, Anesthesia, Postoperative Pain","enrollment":""},{"nctId":"NCT05099055","phase":"PHASE3","title":"Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study","status":"COMPLETED","sponsor":"St. Justine's Hospital","startDate":"2022-03-15","conditions":"Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical","enrollment":42},{"nctId":"NCT05659823","phase":"PHASE4","title":"Postoperative Pain After Caesarian Section","status":"COMPLETED","sponsor":"Conrad Arnfinn Bjørshol","startDate":"2020-11-02","conditions":"Pain, Postoperative, Pruritus, Nausea and Vomiting Following Administration of Anaesthetic Agent","enrollment":108},{"nctId":"NCT03451695","phase":"PHASE4","title":"Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section","status":"COMPLETED","sponsor":"B.P. Koirala Institute of Health Sciences","startDate":"2018-04-01","conditions":"Chronic Pain Post-Procedural","enrollment":290},{"nctId":"NCT00804609","phase":"NA","title":"Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery","status":"COMPLETED","sponsor":"Stanford University","startDate":"2008-09","conditions":"Epidural Analgesia, Obstetric","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Bupivacaine-fentanyl-morphine elective group","genericName":"Bupivacaine-fentanyl-morphine elective group","companyName":"Conrad Arnfinn Bjørshol","companyId":"conrad-arnfinn-bj-rshol","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This is a combination of three analgesic agents—bupivacaine (local anesthetic), fentanyl (opioid), and morphine (opioid)—that work together to provide local anesthesia and systemic pain relief for elective surgical procedures. Used for Perioperative pain management in elective surgical procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}