{"id":"bumadizone","rwe":[{"pmid":"39191859","year":"2024","title":"Innovative voltammetric techniques for bumadizone analysis in pharmaceutical and biological samples: emphasizing green, white, and blue analytical approaches.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"},{"pmid":"28622543","year":"2017","title":"Quantitative analysis of anti-inflammatory drugs using FTIR-ATR spectrometry.","finding":"","journal":"Spectrochimica acta. 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Comparison of the binding of nonsteroid antirheumatics to human serum albumin and their interaction with phenprocoumon].","finding":"","journal":"Archiv der Pharmazie","studyType":"Clinical Study"}],"tags":[{"label":"bumadizone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"M01AB07","category":"atc"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Analgesics, Non-Narcotic","category":"pharmacology"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents, Non-Steroidal","category":"pharmacology"},{"label":"Antirheumatic Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"desflam","offLabel":[],"synonyms":["bumadizone","bumadizon","bumazidone","bumadizone calcium","bumadizone calcium hydrate","bumadizone calcium dihydrate","eumotol","desflam"],"timeline":[],"brandName":"Desflam","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"bumadizone","explanation":"Imagine your body's cells are like a city, and microorganisms are like unwanted visitors. Bumadizone helps keep these visitors from multiplying and taking over by blocking their ability to grow and divide.","oneSentence":"Bumadizone works by inhibiting the growth of microorganisms.","technicalDetail":"Bumadizone exerts its antimicrobial effects by interfering with the synthesis of bacterial DNA, ultimately leading to the inhibition of microbial growth and proliferation."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/426","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BUMADIZONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:08:14.768990","biosimilars":[],"competitors":[{"drugName":"indomethacin","drugSlug":"indomethacin","fdaApproval":"1965-06-10","patentExpiry":"Apr 23, 2030","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"sulindac","drugSlug":"sulindac","fdaApproval":"1978-09-27","genericCount":7,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"tolmetin","drugSlug":"tolmetin","fdaApproval":"1976-03-24","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"diclofenac","drugSlug":"diclofenac","fdaApproval":"1988-07-28","patentExpiry":"Apr 23, 2030","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"etodolac","drugSlug":"etodolac","fdaApproval":"1991-01-31","genericCount":25,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ketorolac","drugSlug":"ketorolac","fdaApproval":"1989-11-30","patentExpiry":"Nov 24, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"aceclofenac","drugSlug":"aceclofenac","fdaApproval":"","relationship":"same-class"}],"genericName":"bumadizone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"indomethacin","brandName":"indomethacin","genericName":"indomethacin","approvalYear":"1965","relationship":"same-class"},{"drugId":"sulindac","brandName":"sulindac","genericName":"sulindac","approvalYear":"1978","relationship":"same-class"},{"drugId":"tolmetin","brandName":"tolmetin","genericName":"tolmetin","approvalYear":"1976","relationship":"same-class"},{"drugId":"diclofenac","brandName":"diclofenac","genericName":"diclofenac","approvalYear":"1988","relationship":"same-class"},{"drugId":"etodolac","brandName":"etodolac","genericName":"etodolac","approvalYear":"1991","relationship":"same-class"},{"drugId":"ketorolac","brandName":"ketorolac","genericName":"ketorolac","approvalYear":"1989","relationship":"same-class"},{"drugId":"aceclofenac","brandName":"aceclofenac","genericName":"aceclofenac","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005444","UNII":"ATD81G944M","CHEBI":"CHEBI:76119","INN_ID":"2847","RXNORM":"19847","UMLSCUI":"C0054219","ChEMBL_ID":"CHEMBL2105456","KEGG_DRUG":"D07264","DRUGBANK_ID":"DB13286","PUBCHEM_CID":"19161","SECONDARY_CAS_RN":"69365-73-7","MESH_SUPPLEMENTAL_RECORD_UI":"C100233"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":25,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"M01AB07","allCodes":["M01AB07"]},"biosimilarFilings":[],"recentPublications":[{"date":"2024 Aug 27","pmid":"39191859","title":"Innovative voltammetric techniques for bumadizone analysis in pharmaceutical and biological samples: emphasizing green, white, and blue analytical approaches.","journal":"Scientific reports"},{"date":"2017 Nov 5","pmid":"28622543","title":"Quantitative analysis of anti-inflammatory drugs using FTIR-ATR spectrometry.","journal":"Spectrochimica acta. 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Comparison of the binding of nonsteroid antirheumatics to human serum albumin and their interaction with phenprocoumon].","journal":"Archiv der Pharmazie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Desflam is a small molecule with synonyms BUMADIZONA, BUMADIZONE, and BUMADIZONE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}