{"id":"bufei-granule","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Allergic reaction"}]},"_chembl":{"chemblId":"CHEMBL564","moleculeType":"Small molecule","molecularWeight":"284.43"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a Chinese herbal granule preparation, Bufei (补肺, meaning 'tonify lung') combines multiple medicinal herbs traditionally used to strengthen lung qi, clear heat, and resolve phlegm. The formulation works through the integrated action of its constituent herbs rather than a single molecular target, consistent with traditional Chinese medicine principles of addressing underlying imbalances in respiratory function.","oneSentence":"Bufei granule is a traditional Chinese medicine formulation that supports lung function and respiratory health through multi-component herbal synergy.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:55:12.034Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic obstructive pulmonary disease (COPD)"},{"name":"Chronic bronchitis"},{"name":"Pulmonary fibrosis"}]},"trialDetails":[{"nctId":"NCT06674252","phase":"NA","title":"A Study on the Improvement of Postoperative Symptoms and Survival Benefits of Modified Bufei Decoction in Elderly Patients With Lung Cancer Undergoing Radical Surgery","status":"RECRUITING","sponsor":"Peking University Cancer Hospital & Institute","startDate":"2025-06-13","conditions":"Lung Cancers","enrollment":174},{"nctId":"NCT06326658","phase":"NA","title":"Bufei Yishen Prescription on Patients With Frequent AECOPD in Stable Stage","status":"NOT_YET_RECRUITING","sponsor":"Henan University of Traditional Chinese Medicine","startDate":"2024-04-01","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":848},{"nctId":"NCT03976700","phase":"PHASE3","title":"Bufei Jianpi Granule for Delaying Pulmonary Function Decline in Early-Stage COPD","status":"UNKNOWN","sponsor":"Henan University of Traditional Chinese Medicine","startDate":"2019-06","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":612},{"nctId":"NCT03976713","phase":"PHASE3","title":"Bufei Yishen Granule for Reducing Acute Exacerbation in GOLD Stage 3 or 4 COPD","status":"UNKNOWN","sponsor":"Henan University of Traditional Chinese Medicine","startDate":"2019-06","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":348},{"nctId":"NCT03443531","phase":"PHASE3","title":"Effects of Traditional Chinese Medicine on Bronchiectasis Patients","status":"UNKNOWN","sponsor":"Henan University of Traditional Chinese Medicine","startDate":"2018-03","conditions":"Bronchiectasis","enrollment":216},{"nctId":"NCT01836016","phase":"PHASE3","title":"A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients","status":"UNKNOWN","sponsor":"Henan University of Traditional Chinese Medicine","startDate":"2013-05","conditions":"Pulmonary Disease, Chronic Obstructive","enrollment":360}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Bufei granule","genericName":"Bufei granule","companyName":"Henan University of Traditional Chinese Medicine","companyId":"henan-university-of-traditional-chinese-medicine","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bufei granule is a traditional Chinese medicine formulation that supports lung function and respiratory health through multi-component herbal synergy. Used for Chronic obstructive pulmonary disease (COPD), Chronic bronchitis, Pulmonary fibrosis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}