{"id":"budesonode-bid-terbutaline-as-needed","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Tremors"},{"rate":"5-10%","effect":"Muscle cramps"},{"rate":"5-10%","effect":"Cough"},{"rate":"5-10%","effect":"Dysphonia"},{"rate":"5-10%","effect":"Oral candidiasis"},{"rate":"1-5%","effect":"Hypokalemia"},{"rate":"1-5%","effect":"Palpitations"},{"rate":"1-5%","effect":"Tachycardia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Budesonide works by inhibiting the production of inflammatory mediators, thereby reducing inflammation in the airways. Terbutaline, on the other hand, stimulates the beta-2 adrenergic receptors, leading to bronchodilation and relaxation of airway smooth muscles.","oneSentence":"Budesonide is a corticosteroid that reduces inflammation, while terbutaline is a beta-2 adrenergic receptor agonist that relaxes airway muscles.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:55:19.652Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Asthma maintenance and control"},{"name":"Chronic obstructive pulmonary disease (COPD) maintenance and control"}]},"trialDetails":[{"nctId":"NCT02224157","phase":"PHASE3","title":"A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma","status":"COMPLETED","sponsor":"AstraZeneca","startDate":"2014-11-28","conditions":"Asthma","enrollment":4215}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":7,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"budesonode bid + terbutaline 'as needed'","genericName":"budesonode bid + terbutaline 'as needed'","companyName":"AstraZeneca","companyId":"astrazeneca","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Budesonide is a corticosteroid that reduces inflammation, while terbutaline is a beta-2 adrenergic receptor agonist that relaxes airway muscles. Used for Asthma maintenance and control, Chronic obstructive pulmonary disease (COPD) maintenance and control.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}