{"id":"bucricaine","rwe":[],"tags":[{"label":"bucricaine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Local anesthesia","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["bucricaine","bucricaine hydrochloride","bucricaine HCl"],"offLabel":[],"synonyms":["bucricaine","bucricaine hydrochloride","bucricaine HCl"],"timeline":[],"ecosystem":[{"indication":"Local anesthesia","otherDrugs":[{"name":"amobarbital","slug":"amobarbital","company":""},{"name":"benzalkonium","slug":"benzalkonium","company":""},{"name":"benzocaine","slug":"benzocaine","company":""},{"name":"bupivacaine","slug":"bupivacaine","company":"Hospira"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"bucricaine","explanation":"Imagine your nerves are like electrical wires, carrying signals to and from your brain. Bucricaine blocks these wires, stopping the pain signals from getting through. This numbs the area, making it less sensitive to pain.","oneSentence":"Bucricaine works by blocking sodium channels in nerve cells, preventing the transmission of pain signals.","technicalDetail":"Bucricaine acts as a sodium channel blocker, inhibiting the influx of sodium ions into nerve cells, which is essential for the initiation and transmission of action potentials."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3884","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BUCRICAINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:04:30.805215","biosimilars":[],"competitors":[],"genericName":"bucricaine","indications":{"approved":[{"name":"Local anesthesia","source":"DrugCentral","snomedId":386761002,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"HUC352BGYM","CHEBI":"CHEBI:135040","INN_ID":"5353","UMLSCUI":"C2347225","ChEMBL_ID":"CHEMBL2106141","PUBCHEM_CID":"9423","SECONDARY_CAS_RN":"82636-28-0"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"BUCRICAINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bucricaine is a small molecule drug in the bucricaine class, used for local anesthesia. Its exact target is unknown, but it is effective in numbing specific areas of the body. Bucricaine is approved for use in local anesthesia, but its commercial status and regulatory approvals are unclear. As a local anesthetic, bucricaine works by blocking nerve signals, preventing pain and discomfort. Further information on its pharmacokinetics and safety profile is needed.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}