{"id":"buclosamide","rwe":[{"pmid":"29182340","year":"2018","title":"Metal-Free Thermal Activation of Molecular Oxygen Enabled Direct α-CH(2)-Oxygenation of Free Amines.","finding":"","journal":"The Journal of organic chemistry","studyType":"Clinical Study"},{"pmid":"6839737","year":"1983","title":"Studies on purity and stability of photopatch test substances.","finding":"","journal":"Contact dermatitis","studyType":"Clinical Study"},{"pmid":"4426634","year":"1974","title":"Topical therapy with Jadit (buclosamide) in dermatomycoses.","finding":"","journal":"Indian journal of dermatology","studyType":"Clinical Study"},{"pmid":"5416802","year":"1970","title":"Persistent light reactions from buclosamide.","finding":"","journal":"Archives of dermatology","studyType":"Clinical Study"},{"pmid":"4914369","year":"1970","title":"A clinical trial with a new topical antimycotic agent 4-chloro-2-hydroxybenzoic acid-n-butylmide i.e. buclosamide.","finding":"","journal":"Indian journal of dermatology","studyType":"Clinical Study"}],"tags":[{"label":"buclosamide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"demycin","offLabel":[],"synonyms":["buclosamide","demycin","N-Butyl-4-chlorosalicylamide"],"timeline":[],"brandName":"Demycin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"buclosamide","explanation":"Imagine your cells are like a orchestra, and Demycin is a conductor that helps the different sections work together in harmony. By adjusting the way these cellular components communicate, Demycin can help restore balance and alleviate symptoms. This process is complex and involves many molecular interactions.","oneSentence":"Demycin works by interacting with a specific cellular target to modulate its activity.","technicalDetail":"Demycin is a small molecule that binds to a specific protein or receptor, altering its function and leading to downstream effects on cellular signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3043","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BUCLOSAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:04:22.691634","biosimilars":[],"competitors":[],"genericName":"buclosamide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"O52NM0A9YL","CHEBI":"CHEBI:134935","INN_ID":"2146","UMLSCUI":"C0162967","ChEMBL_ID":"CHEMBL348251","PUBCHEM_CID":"68466","MESH_SUPPLEMENTAL_RECORD_UI":"C006831"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":5,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2018 Jan 5","pmid":"29182340","title":"Metal-Free Thermal Activation of Molecular Oxygen Enabled Direct α-CH(2)-Oxygenation of Free Amines.","journal":"The Journal of organic chemistry"},{"date":"1983 Jan","pmid":"6839737","title":"Studies on purity and stability of photopatch test substances.","journal":"Contact dermatitis"},{"date":"1974 Apr","pmid":"4426634","title":"Topical therapy with Jadit (buclosamide) in dermatomycoses.","journal":"Indian journal of dermatology"},{"date":"1970 Jan","pmid":"5416802","title":"Persistent light reactions from buclosamide.","journal":"Archives of dermatology"},{"date":"1970 Jan","pmid":"4914369","title":"A clinical trial with a new topical antimycotic agent 4-chloro-2-hydroxybenzoic acid-n-butylmide i.e. buclosamide.","journal":"Indian journal of dermatology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Demycin, also known as buclosamide, is a small molecule drug in the buclosamide class. Its exact target is unknown, but it is used to treat certain conditions. Demycin's commercial status is unclear, and it may be patented or have generic manufacturers. Key safety considerations are not well-documented. Further research is needed to fully understand Demycin's properties and uses.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}