{"id":"bt-ktm-i","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Dizziness"}]},"_chembl":{"chemblId":"CHEMBL1909400","moleculeType":"Small molecule","molecularWeight":"557.55"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting PDE3, BT-KTM-I increases the levels of cyclic AMP, leading to vasodilation and improved cardiac function.","oneSentence":"BT-KTM-I is a small molecule that targets the PDE3 enzyme.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:52:56.809Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute heart failure"}]},"trialDetails":[{"nctId":"NCT06092684","phase":"PHASE3","title":"The Efficacy and Safety of Esketamine in Elective Laparoscopic Surgery","status":"COMPLETED","sponsor":"Chengdu Brilliant Pharmaceutical Co., Ltd.","startDate":"2023-09-20","conditions":"Laparoscopy, Anesthesia, Intravenous","enrollment":358}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Esketamine"],"phase":"phase_3","status":"active","brandName":"BT-KTM-I","genericName":"BT-KTM-I","companyName":"Chengdu Brilliant Pharmaceutical Co., Ltd.","companyId":"chengdu-brilliant-pharmaceutical-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BT-KTM-I is a medication being studied in a clinical trial for its efficacy and safety in elective laparoscopic surgery. The trial compares BT-KTM-I to Ketanest S, another medication, in a randomized, double-blind study.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}