{"id":"brovincamine","rwe":[{"pmid":"39385332","year":"2025","title":"Comparative analysis of medical treatments for long-term control of normal tension glaucoma: A systematic review and model-based network meta-analysis.","finding":"","journal":"Clinical & experimental ophthalmology","studyType":"Clinical Study"},{"pmid":"20933604","year":"2011","title":"Use of calcium channel blockers for glaucoma.","finding":"","journal":"Progress in retinal and eye research","studyType":"Clinical Study"},{"pmid":"20166063","year":"2010","title":"WITHDRAWN: Interventions for normal tension glaucoma.","finding":"","journal":"The Cochrane database of systematic reviews","studyType":"Clinical Study"},{"pmid":"14583947","year":"2003","title":"Interventions for normal tension glaucoma.","finding":"","journal":"The Cochrane database of systematic reviews","studyType":"Clinical Study"},{"pmid":"11802456","year":"2001","title":"[Open-angle glaucoma clinical presentation and management].","finding":"","journal":"Nippon Ganka Gakkai zasshi","studyType":"Clinical Study"}],"tags":[{"label":"brovincamine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Vasodilator Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"11-brovincamine","offLabel":[],"synonyms":["brovincamine","11-Bromovincamine","11-Brovincamine","cis-11-Bromovincamine"],"timeline":[],"brandName":"11-Brovincamine","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"brovincamine","explanation":"Think of BROVINCAMINE like a key that unlocks a specific process in the body. By fitting into a particular spot, it can influence how the body works, but the exact details of how it does this are still unclear. This process can potentially lead to changes in how the body functions, but more research is needed to understand the full effects.","oneSentence":"BROVINCAMINE is believed to work by modulating certain biological pathways.","technicalDetail":"The exact mechanism of action of BROVINCAMINE is unknown, but it is thought to interact with specific biological targets to produce its effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/411","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BROVINCAMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:07:19.768085","biosimilars":[],"competitors":[],"genericName":"brovincamine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"AYN5T18K5R","CHEBI":"CHEBI:135701","INN_ID":"4679","UMLSCUI":"C0044725","ChEMBL_ID":"CHEMBL165643","KEGG_DRUG":"D07545","PUBCHEM_CID":"68771","MESH_SUPPLEMENTAL_RECORD_UI":"C033581"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":25,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2025 Jan-Feb","pmid":"39385332","title":"Comparative analysis of medical treatments for long-term control of normal tension glaucoma: A systematic review and model-based network meta-analysis.","journal":"Clinical & experimental ophthalmology"},{"date":"2011 Jan","pmid":"20933604","title":"Use of calcium channel blockers for glaucoma.","journal":"Progress in retinal and eye research"},{"date":"2010 Feb 17","pmid":"20166063","title":"WITHDRAWN: Interventions for normal tension glaucoma.","journal":"The Cochrane database of systematic reviews"},{"date":"2003","pmid":"14583947","title":"Interventions for normal tension glaucoma.","journal":"The Cochrane database of systematic reviews"},{"date":"2001 Dec","pmid":"11802456","title":"[Open-angle glaucoma clinical presentation and management].","journal":"Nippon Ganka Gakkai zasshi"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BROVINCAMINE, also known as 11-Brovincamine, is a small molecule drug in the brovincamine class. Its exact target and mechanism of action are unknown, but it is believed to work by modulating certain biological pathways. BROVINCAMINE is not FDA-approved for any indications, and its commercial status, including patent and generic availability, is unclear. Further research is needed to determine its safety and efficacy. As a result, key safety considerations and approved indications are currently unavailable.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}