{"id":"bromoform","rwe":[{"pmid":"41893537","year":"2026","title":"Metabolic Disruption and Steatosis Induced by Drinking Water Disinfection Byproducts in HepG2 and HUH7 Cells.","finding":"","journal":"Toxics","studyType":"Clinical Study"},{"pmid":"41679636","year":"2026","title":"Dose-dependent effects of the Asparagopsis taxiformis variety Brominata on enteric methane emissions of dairy cows.","finding":"","journal":"Journal of dairy science","studyType":"Clinical Study"},{"pmid":"41679627","year":"2026","title":"Enteric methane production in response to direct ruminal infusion of synthetic bromoform in cattle.","finding":"","journal":"Journal of dairy science","studyType":"Clinical Study"},{"pmid":"41663381","year":"2026","title":"Ultrafast solvent-modulated roaming mechanism in bromoform revealed by femtosecond X-ray solution scattering.","finding":"","journal":"Nature communications","studyType":"Clinical Study"},{"pmid":"41651895","year":"2026","title":"Risk assessment of trihalomethanes in drinking water with seasonal variation considerations.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Carcinogens","category":"pharmacology"},{"label":"Noxae","category":"pharmacology"},{"label":"Teratogens","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tribromomethane","offLabel":[],"synonyms":["bromoform","methenyl tribromide","tribromomethane"],"timeline":[],"brandName":"Tribromomethane","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and the key to unlocking a specific lock is a molecule that fits perfectly. Tribromomethane is like a key that binds to a specific lock, allowing it to influence the behavior of the cell. This interaction can help to treat certain diseases or conditions, but it can also have unintended consequences if not used carefully.","oneSentence":"Tribromomethane works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Tribromomethane's mechanism of action is not well-characterized, but it is likely to involve the modulation of a specific protein or enzyme, leading to changes in cellular signaling pathways and ultimately affecting disease-related processes."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Bromoform","title":"Bromoform","extract":"Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/405","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=bromoform","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Bromoform","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:02:56.110365","biosimilars":[],"competitors":[],"genericName":"bromoform","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"NOCODE","NDDF":"005242","UNII":"TUT9J99IMU","CHEBI":"CHEBI:38682","UMLSCUI":"C0054122","ChEMBL_ID":"CHEMBL345248","DRUGBANK_ID":"DB03054","PDB_CHEM_ID":" B4M","PUBCHEM_CID":"5558","MESH_SUPPLEMENTAL_RECORD_UI":"C015044"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":564,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 21","pmid":"41893537","title":"Metabolic Disruption and Steatosis Induced by Drinking Water Disinfection Byproducts in HepG2 and HUH7 Cells.","journal":"Toxics"},{"date":"2026 Feb 10","pmid":"41679636","title":"Dose-dependent effects of the Asparagopsis taxiformis variety Brominata on enteric methane emissions of dairy cows.","journal":"Journal of dairy science"},{"date":"2026 Feb 10","pmid":"41679627","title":"Enteric methane production in response to direct ruminal infusion of synthetic bromoform in cattle.","journal":"Journal of dairy science"},{"date":"2026 Feb 9","pmid":"41663381","title":"Ultrafast solvent-modulated roaming mechanism in bromoform revealed by femtosecond X-ray solution scattering.","journal":"Nature communications"},{"date":"2026 Feb 6","pmid":"41651895","title":"Risk assessment of trihalomethanes in drinking water with seasonal variation considerations.","journal":"Scientific reports"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Tribromomethane, also known as bromoform, is a small molecule compound with unknown target and drug class. Its commercial status is unclear, and it is not FDA-approved for any indications. As a small molecule, it is likely to be administered orally or through injection, but its pharmacokinetic properties, such as half-life and bioavailability, are unknown. The compound's safety profile and potential side effects are also not well-documented. Further research is needed to understand its potential therapeutic applications and risks.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}