{"id":"brm424-ophthalmic-solution-dose1","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Eye irritation"}]},"_chembl":{"chemblId":"CHEMBL2108251","moleculeType":"Oligosaccharide"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"BRM424 Ophthalmic Solution works by reducing inflammation in the eye, which can help alleviate symptoms of certain eye conditions. The exact molecular target is not publicly disclosed, but it is believed to involve the inhibition of pro-inflammatory pathways.","oneSentence":"BRM424 Ophthalmic Solution is a topical anti-inflammatory agent.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:57:37.356Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of dry eye disease"}]},"trialDetails":[{"nctId":"NCT05927428","phase":"PHASE2","title":"Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis","status":"RECRUITING","sponsor":"BRIM Biotechnology Inc.","startDate":"2024-07-31","conditions":"Neurotrophic Keratitis","enrollment":12}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"BRM424 Ophthalmic Solution - Dose1","genericName":"BRM424 Ophthalmic Solution - Dose1","companyName":"BRIM Biotechnology Inc.","companyId":"brim-biotechnology-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BRM424 Ophthalmic Solution is a topical anti-inflammatory agent. Used for Treatment of dry eye disease.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}