{"id":"br5402a-1","safety":{"commonSideEffects":[{"rate":"null","effect":"Muscle pain"},{"rate":"null","effect":"Liver enzyme elevation"}]},"_chembl":{"chemblId":"CHEMBL3301587","moleculeType":"Antibody"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting HMG-CoA reductase, BR5402A-1 aims to reduce cholesterol production in the liver, thereby lowering low-density lipoprotein (LDL) cholesterol levels. This mechanism is similar to that of statins, but BR5402A-1 may have a different pharmacokinetic profile and potentially fewer side effects.","oneSentence":"BR5402A-1 is a small molecule that targets the HMG-CoA reductase enzyme.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:57:38.076Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypercholesterolemia"}]},"trialDetails":[{"nctId":"NCT06821945","phase":"PHASE2","title":"A Clinical Trial to Evaluate the Safety and Efficacy of Olanzapine Titration Schedule in Patients With Schizophrenia","status":"RECRUITING","sponsor":"Boryung Pharmaceutical Co., Ltd","startDate":"2025-05-30","conditions":"Schizophrenia","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Placebo of BR5402A"],"phase":"phase_2","status":"active","brandName":"BR5402A-1","genericName":"BR5402A-1","companyName":"Boryung Pharmaceutical Co., Ltd","companyId":"boryung-pharmaceutical-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BR5402A-1 is a small molecule that targets the HMG-CoA reductase enzyme. Used for Hypercholesterolemia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}