{"id":"botulinum-toxin-type-b","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or bruising"},{"rate":null,"effect":"Muscle weakness or paralysis (off-target)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Flu-like symptoms"},{"rate":null,"effect":"Antibody formation (neutralizing antibodies)"}]},"_chembl":null,"_dailymed":{"setId":"3aaa6e14-a3f7-4fb2-b9f9-d3a9c3ae1f74","title":"DAXXIFY (BOTULINUM TOXIN TYPE A) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [REVANCE THERAPEUTICS, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Botulinum toxin type B is a neurotoxin that cleaves synaptobrevin (VAMP), a protein essential for acetylcholine vesicle fusion and release at the neuromuscular junction. This prevents acetylcholine from being released into the synaptic cleft, resulting in temporary paralysis of the targeted muscle. The effect is reversible as the body gradually regenerates new SNARE proteins over several months.","oneSentence":"Botulinum toxin type B blocks acetylcholine release at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:28:09.957Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cervical dystonia"},{"name":"Blepharospasm"},{"name":"Strabismus"},{"name":"Hyperhidrosis"},{"name":"Migraine prophylaxis"},{"name":"Spasticity"}]},"trialDetails":[{"nctId":"NCT07018700","phase":"PHASE3","title":"A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic Migraine","status":"RECRUITING","sponsor":"Merz Therapeutics GmbH","startDate":"2025-08-21","conditions":"Episodic Migraine","enrollment":990},{"nctId":"NCT07018713","phase":"PHASE3","title":"A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing 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