{"id":"botox-tend","safety":{"commonSideEffects":[{"rate":null,"effect":"Muscle weakness"},{"rate":null,"effect":"Pain at injection site"},{"rate":null,"effect":"Localized hematoma"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The drug likely works by inhibiting acetylcholine release at the neuromuscular junction, reducing muscle hyperactivity and spasticity around affected tendons. This mechanism may alleviate pain, improve mobility, and promote healing in tendon-related pathologies by decreasing abnormal muscle tension and load on the affected tissue.","oneSentence":"Botox-Tend is a botulinum toxin-based therapeutic designed to reduce muscle tension and improve tendon function through localized neuromuscular blockade.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:42:11.236Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Tendon disorders with associated muscle hyperactivity (specific indication under investigation in phase 3)"}]},"trialDetails":[{"nctId":"NCT02767635","phase":"PHASE3","title":"Comparison Between Steroid and Different Sites of Botulinum Toxin Injection in the Treatment of Lateral Epicondylalgia","status":"UNKNOWN","sponsor":"National Cheng-Kung University Hospital","startDate":"2012-01","conditions":"Tennis Elbow","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["onabotulinumtoxinA"],"phase":"phase_3","status":"active","brandName":"Botox-Tend","genericName":"Botox-Tend","companyName":"National Cheng-Kung University Hospital","companyId":"national-cheng-kung-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Botox-Tend is a botulinum toxin-based therapeutic designed to reduce muscle tension and improve tendon function through localized neuromuscular blockade. Used for Tendon disorders with associated muscle hyperactivity (specific indication under investigation in phase 3).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}