{"id":"bleomycin-fibrovein","safety":{"commonSideEffects":[{"rate":null,"effect":"Pulmonary fibrosis"},{"rate":null,"effect":"Skin toxicity"},{"rate":null,"effect":"Mucositis"},{"rate":null,"effect":"Hematologic toxicity"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bleomycin intercalates into DNA and causes strand breaks, leading to cell death in rapidly dividing cancer cells. Fibrovein is a topical hemostatic agent composed of fibrinogen and thrombin that promotes clotting. This combination is used intraoperatively to deliver bleomycin while simultaneously controlling hemorrhage at the surgical site.","oneSentence":"Bleomycin is a chemotherapeutic antibiotic that damages DNA, while Fibrovein is a fibrin-based hemostatic agent used to control bleeding during surgical application of bleomycin.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:28:41.944Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Intraoperative hemostasis and local chemotherapy delivery during cancer surgery"}]},"trialDetails":[{"nctId":"NCT01347294","phase":"PHASE4","title":"Compare Two Different Sclerosing Agents in the Treatment of Venous Malformations","status":"UNKNOWN","sponsor":"Oslo University Hospital","startDate":"2011-08","conditions":"Venous Malformation","enrollment":135}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Bleomycin Baxter + Fibrovein pharmaceutical products"],"phase":"marketed","status":"active","brandName":"Bleomycin + Fibrovein","genericName":"Bleomycin + Fibrovein","companyName":"Oslo University Hospital","companyId":"oslo-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bleomycin is a chemotherapeutic antibiotic that damages DNA, while Fibrovein is a fibrin-based hemostatic agent used to control bleeding during surgical application of bleomycin. Used for Intraoperative hemostasis and local chemotherapy delivery during cancer surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}