{"id":"bladder-instillation-without-triamcinolone-acetonide","safety":{"commonSideEffects":[{"rate":null,"effect":"Dysuria"},{"rate":null,"effect":"Urinary frequency"},{"rate":null,"effect":"Bladder spasm"},{"rate":null,"effect":"Hematuria"}]},"_chembl":{"chemblId":"CHEMBL1504","moleculeType":"Small molecule","molecularWeight":"434.50"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bladder instillation is a local delivery method where medication is introduced directly into the bladder via catheter, allowing high local concentrations while minimizing systemic exposure. This formulation specifically excludes triamcinolone acetonide (a corticosteroid), suggesting it may contain alternative active agents or be a vehicle/comparator formulation. The direct instillation approach is commonly used for interstitial cystitis, bladder pain syndrome, and recurrent urinary tract infections.","oneSentence":"A bladder instillation therapy that delivers therapeutic agents directly into the bladder without triamcinolone acetonide to treat bladder conditions.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:04:27.505Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bladder pain syndrome / Interstitial cystitis (likely primary indication)"}]},"trialDetails":[{"nctId":"NCT03463915","phase":"PHASE3","title":"Clinical Trial Comparing Two Bladder Instillations for IC/BPS","status":"COMPLETED","sponsor":"Olivia Cardenas-Trowers, M.D.","startDate":"2019-01-25","conditions":"Interstitial Cystitis, Bladder Pain Syndrome","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Bladder instillation WITHOUT triamcinolone acetonide","genericName":"Bladder instillation WITHOUT triamcinolone acetonide","companyName":"Olivia Cardenas-Trowers, M.D.","companyId":"olivia-cardenas-trowers-m-d","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A bladder instillation therapy that delivers therapeutic agents directly into the bladder without triamcinolone acetonide to treat bladder conditions. Used for Bladder pain syndrome / Interstitial cystitis (likely primary indication).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}