{"id":"bitoscanate","rwe":[{"pmid":"16076531","year":"2005","title":"Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds.","finding":"","journal":"Veterinary parasitology","studyType":"Clinical Study"},{"pmid":"955553","year":"1976","title":"[Worm-diseases].","finding":"","journal":"Fortschritte der Medizin","studyType":"Clinical Study"},{"pmid":"769080","year":"1975","title":"Clinical experience with bitoscanate.","finding":"","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques","studyType":"Clinical Study"},{"pmid":"769079","year":"1975","title":"Experience with bitoscanate in adults.","finding":"","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques","studyType":"Clinical Study"},{"pmid":"769078","year":"1975","title":"Comparative study of bitoscanate, bephenium hydroxynaphthoate and tetrachlorethylene in hookworm disease.","finding":"","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bitoscanat","offLabel":[],"synonyms":["bitoscanate","1,4-Diisothiocyanatobenzene","bitoscanat","p-Phenylene bisisothiocyanate"],"timeline":[],"brandName":"Bitoscanat","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a city with many different buildings. Bitoscanate is like a key that fits into a specific lock on one of those buildings, allowing it to work properly and helping to treat a particular condition. However, the exact lock and building it targets are still unknown.","oneSentence":"Bitoscanate works by binding to specific biological molecules to produce a therapeutic effect.","technicalDetail":"As a small molecule, Bitoscanate likely works by interacting with a specific protein or receptor, altering its function and leading to a therapeutic effect. However, the precise molecular mechanism and target of Bitoscanate are currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3033","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=BITOSCANATE","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BITOSCANATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:01:39.159336","biosimilars":[],"competitors":[],"genericName":"bitoscanate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT06081088","phase":"NA","title":"Graded Motor Imagery Training in Shoulder Impingement Syndrome","status":"COMPLETED","sponsor":"Marmara University","startDate":"2023-10-16","conditions":["Shoulder Impingement Syndrome","Pain"],"enrollment":42,"completionDate":"2024-06-27"},{"nctId":"NCT01618032","phase":"NA","title":"Effects of Two Techniques of Mobilization in the Dorsiflexion on Patients With Chronic Ankle Instability","status":"COMPLETED","sponsor":"CEU San Pablo University","startDate":"2010-11","conditions":["Chronic Instability of Joint"],"enrollment":52,"completionDate":"2012-11"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"6D1R3P86GX","CHEBI":"CHEBI:134845","INN_ID":"2397","UMLSCUI":"C0053818","ChEMBL_ID":"CHEMBL2104676","PUBCHEM_CID":"19958","MESH_SUPPLEMENTAL_RECORD_UI":"C032582"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":19,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2005 Nov 25","pmid":"16076531","title":"Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds.","journal":"Veterinary parasitology"},{"date":"1976 Jul 15","pmid":"955553","title":"[Worm-diseases].","journal":"Fortschritte der Medizin"},{"date":"1975","pmid":"769080","title":"Clinical experience with bitoscanate.","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques"},{"date":"1975","pmid":"769079","title":"Experience with bitoscanate in adults.","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques"},{"date":"1975","pmid":"769078","title":"Comparative study of bitoscanate, bephenium hydroxynaphthoate and tetrachlorethylene in hookworm disease.","journal":"Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bitoscanate is a small molecule with the synonyms BITOSCANATE, BITOSCANATO, NSC-758884, and P-PHENYLENE BIS(ISOTHIOCYANATE).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}