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This personalized, susceptibility-guided strategy aims to improve eradication rates compared to empirical standard regimens.","oneSentence":"Bismuth-based susceptibility-guided treatment uses antimicrobial susceptibility testing to direct personalized bismuth-containing regimens for Helicobacter pylori eradication.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:21:13.869Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Helicobacter pylori infection (susceptibility-guided eradication)"}]},"trialDetails":[{"nctId":"NCT07405684","phase":"PHASE4","title":"Fecal Molecular Susceptibility-guided Hp First-line Therapy","status":"NOT_YET_RECRUITING","sponsor":"Shanghai Zhongshan Hospital","startDate":"2026-02-28","conditions":"HELICOBACTER PYLORI INFECTIONS","enrollment":544},{"nctId":"NCT07405697","phase":"PHASE4","title":"Fecal Molecular Susceptibility-guided Hp Rescue Therapy","status":"NOT_YET_RECRUITING","sponsor":"Shanghai Zhongshan Hospital","startDate":"2026-02-28","conditions":"Helicobacter Pylori Infection","enrollment":290},{"nctId":"NCT05332444","phase":"PHASE4","title":"Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection","status":"RECRUITING","sponsor":"National Taiwan University Hospital","startDate":"2022-04-11","conditions":"Helicobacter Pylori Infection","enrollment":450},{"nctId":"NCT04332848","phase":"PHASE4","title":"Susceptibility Testing Guided Versus Empirical Therapy for Refractory H. 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Pylori Infection","status":"COMPLETED","sponsor":"National Cheng-Kung University Hospital","startDate":"2022-08-22","conditions":"Helicobacter Pylori, Drug Resistance, Multiple","enrollment":46},{"nctId":"NCT02373280","phase":"NA","title":"The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection","status":"UNKNOWN","sponsor":"Seoul National University Bundang Hospital","startDate":"2014-08","conditions":"Helicobacter Infection","enrollment":600},{"nctId":"NCT02359331","phase":"NA","title":"The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. 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Pylori","status":"UNKNOWN","sponsor":"National Taiwan University Hospital","startDate":"2018-03-29","conditions":"Helicobacter Pylori Infection","enrollment":560},{"nctId":"NCT03571230","phase":"PHASE4","title":"Antimicrobial Susceptibility Testing Guided Therapy Versus Empirical Therapy for the First-line Helicobacter Pylori Eradication.","status":"UNKNOWN","sponsor":"Shandong University","startDate":"2018-07-01","conditions":"Helicobacter Pylori Infection, Antimicrobial Susceptibility Testing","enrollment":400},{"nctId":"NCT02988089","phase":"PHASE4","title":"Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment","status":"UNKNOWN","sponsor":"Shandong University","startDate":"2017-04-20","conditions":"Helicobacter Pylori Infection, Antimicrobial Susceptibility Testing","enrollment":480},{"nctId":"NCT02759029","phase":"NA","title":"Development of Treatment Algorithm for Eradication of Helicobacter Pylori Based on Antibiotic Susceptibility Test","status":"UNKNOWN","sponsor":"Gangnam Severance Hospital","startDate":"2016-03","conditions":"Helicobacter Pylori Infection","enrollment":123}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Bismuth-based susceptibility-guided treatment","genericName":"Bismuth-based susceptibility-guided treatment","companyName":"National Cheng-Kung University Hospital","companyId":"national-cheng-kung-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bismuth-based susceptibility-guided treatment uses antimicrobial susceptibility testing to direct personalized bismuth-containing regimens for Helicobacter pylori eradication. Used for Helicobacter pylori infection (susceptibility-guided eradication).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}