{"id":"bisacodyl-5-milligram","safety":{"commonSideEffects":[{"rate":null,"effect":"Abdominal cramping"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Electrolyte imbalance"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Bisacodyl is a diphenylmethane laxative that acts as a contact laxative. It is converted by colonic bacteria to its active metabolite, which directly stimulates the smooth muscle of the colon and inhibits water and electrolyte reabsorption in the intestine, thereby increasing stool bulk and promoting defecation.","oneSentence":"Bisacodyl stimulates colonic muscle contractions and increases intestinal fluid secretion to promote bowel evacuation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:28:37.929Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Constipation"},{"name":"Bowel evacuation prior to diagnostic procedures"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[{"count":1,"reaction":"BODY HEIGHT DECREASED"},{"count":1,"reaction":"DIARRHOEA"},{"count":1,"reaction":"DRUG INEFFECTIVE"}],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["dulcolax"],"phase":"marketed","status":"active","brandName":"Bisacodyl 5 milligram","genericName":"Bisacodyl 5 milligram","companyName":"University of Nottingham","companyId":"university-of-nottingham","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bisacodyl stimulates colonic muscle contractions and increases intestinal fluid secretion to promote bowel evacuation. Used for Constipation, Bowel evacuation prior to diagnostic procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}