{"id":"biphenylol","rwe":[{"pmid":"41411973","year":"2026","title":"Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis.","finding":"","journal":"Environment international","studyType":"Clinical Study"},{"pmid":"38198870","year":"2024","title":"NeuTox: A weighted ensemble model for screening potential neuronal cytotoxicity of chemicals based on various types of molecular representations.","finding":"","journal":"Journal of hazardous materials","studyType":"Clinical Study"},{"pmid":"34082026","year":"2021","title":"First insight on in vitro metabolism of three newly identified aryl organophosphate esters via a suspect coupled with nontarget screening approach.","finding":"","journal":"Toxicology letters","studyType":"Clinical Study"},{"pmid":"33515888","year":"2021","title":"Newly discovered bis-(2-ethylhexyl)-phenyl phosphate (BEHPP) was a ubiquitous contaminant in surface soils from a typical region, South China.","finding":"","journal":"The Science of the total environment","studyType":"Clinical Study"},{"pmid":"31635002","year":"2019","title":"Distribution of flame retardants in smartphones and identification of current-use organic chemicals including three novel aryl organophosphate esters.","finding":"","journal":"The Science of the total environment","studyType":"Clinical Study"}],"tags":[{"label":"biphenylol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D08AE06","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"preventol","offLabel":[],"synonyms":["biphenylol","2-Biphenylol","preventol"],"timeline":[],"brandName":"Preventol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"biphenylol","explanation":"Imagine your body's cells have locks on them, and Preventol is a key that fits into those locks. When it binds to the lock, it triggers a series of events that help to treat a particular condition. This is a simplified explanation of how Preventol works at a molecular level.","oneSentence":"Preventol works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Preventol's mechanism of action involves binding to a specific receptor or enzyme, which triggers a cascade of downstream effects that ultimately lead to its therapeutic effects."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/2-Phenylphenol","title":"2-Phenylphenol","extract":"2-Phenylphenol, or o-phenylphenol, is an organic compound with the formula C6H5−C6H4OH. It is one of three isomers of monohydroxylated biphenyl. It is a white solid. It is a biocide used as a preservative with E number E231 and under the trade names Dowicide, Torsite, Fungal, Preventol, Nipacide and many others."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4768","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=biphenylol","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/2-Phenylphenol","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T09:03:42.390409","biosimilars":[],"competitors":[{"drugName":"hexachlorophene","drugSlug":"hexachlorophene","fdaApproval":"1949-04-19","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"phenol","drugSlug":"phenol","fdaApproval":"","relationship":"same-class"},{"drugName":"triclosan","drugSlug":"triclosan","fdaApproval":"1997-07-11","relationship":"same-class"},{"drugName":"chloroxylenol","drugSlug":"chloroxylenol","fdaApproval":"","relationship":"same-class"}],"genericName":"biphenylol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"hexachlorophene","brandName":"hexachlorophene","genericName":"hexachlorophene","approvalYear":"1949","relationship":"same-class"},{"drugId":"phenol","brandName":"phenol","genericName":"phenol","approvalYear":"","relationship":"same-class"},{"drugId":"triclosan","brandName":"triclosan","genericName":"triclosan","approvalYear":"1997","relationship":"same-class"},{"drugId":"chloroxylenol","brandName":"chloroxylenol","genericName":"chloroxylenol","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"0816G78TY1","CHEBI":"CHEBI:17043","UMLSCUI":"C3652925","DRUGBANK_ID":"DB13734","PDB_CHEM_ID":"CH9","PUBCHEM_CID":"7017"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":65,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"D08AE06","allCodes":["D08AE06"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Jan","pmid":"41411973","title":"Co-exposure to PFAS and hydroxylated PCBs is associated with increased odds of multiple sclerosis.","journal":"Environment international"},{"date":"2024 Mar 5","pmid":"38198870","title":"NeuTox: A weighted ensemble model for screening potential neuronal cytotoxicity of chemicals based on various types of molecular representations.","journal":"Journal of hazardous materials"},{"date":"2021 Sep 15","pmid":"34082026","title":"First insight on in vitro metabolism of three newly identified aryl organophosphate esters via a suspect coupled with nontarget screening approach.","journal":"Toxicology letters"},{"date":"2021 May 20","pmid":"33515888","title":"Newly discovered bis-(2-ethylhexyl)-phenyl phosphate (BEHPP) was a ubiquitous contaminant in surface soils from a typical region, South China.","journal":"The Science of the total environment"},{"date":"2019 Nov 25","pmid":"31635002","title":"Distribution of flame retardants in smartphones and identification of current-use organic chemicals including three novel aryl organophosphate esters.","journal":"The Science of the total environment"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Preventol is a biocide used as a preservative with the chemical formula C6H5−C6H4OH, also known as 2-Phenylphenol or o-phenylphenol. It is a white solid and one of the trade names for the compound 2-Phenylphenol, which is used under various names including E231.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}