{"id":"bezitramide","rwe":[],"tags":[{"label":"bezitramide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N02AC05","category":"atc"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"burgodin","offLabel":[],"synonyms":["R-4845","bezitramide monohydrochloride","bezitramide hydrochloride","bezitramide HCl","bezitramide","benzitramide","burgodin"],"timeline":[],"brandName":"Burgodin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"bezitramide","explanation":"Think of ion channels like gates that control the flow of tiny particles called ions in and out of cells. When these gates are open or closed, it can affect how cells work and communicate with each other. Burgodin is thought to affect the way these gates work, but the exact details of how it does this are still unclear.","oneSentence":"Burgodin works by modulating ion channels in the body.","technicalDetail":"Burgodin is a small molecule that binds to and modulates the activity of certain ion channels, specifically the T-type calcium channels, which play a role in regulating neuronal excitability and neurotransmitter release."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/363","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BEZITRAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:59:25.298723","biosimilars":[],"competitors":[{"drugName":"dextropropoxyphene","drugSlug":"dextropropoxyphene","fdaApproval":"1957-08-16","relationship":"same-class"},{"drugName":"methadone","drugSlug":"methadone","fdaApproval":"1947-08-13","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"bezitramide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"dextropropoxyphene","brandName":"dextropropoxyphene","genericName":"dextropropoxyphene","approvalYear":"1957","relationship":"same-class"},{"drugId":"methadone","brandName":"methadone","genericName":"methadone","approvalYear":"1947","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"3KXW0Y310I","CHEBI":"CHEBI:135794","INN_ID":"1942","UMLSCUI":"C0053535","ChEMBL_ID":"CHEMBL2104149","KEGG_DRUG":"D07289","DRUGBANK_ID":"DB01459","PUBCHEM_CID":"61791","SECONDARY_CAS_RN":"59708-44-0","MESH_SUPPLEMENTAL_RECORD_UI":"C004461"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":22,"therapeuticAreas":["Neuroscience"],"atcClassification":{"source":"DrugCentral","atcCode":"N02AC05","allCodes":["N02AC05"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Burgodin, also known as bezitramide, is a small molecule drug of the bezitramide class. Its exact target and mechanism of action are unknown, but it is believed to work by modulating certain ion channels in the body. Burgodin's commercial status and approved indications are unclear, and it is not known whether it is patented or available as a generic medication. Further research is needed to fully understand its effects and potential uses. As a result, key safety considerations and pharmacokinetic properties, such as half-life and bioavailability, are also unknown.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}