{"id":"betamethasone-dipropionate-aerosol-spray","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin atrophy"},{"rate":"null","effect":"Hypersensitivity reactions"}]},"_chembl":{"chemblId":"CHEMBL3138708","moleculeType":"Small molecule","molecularWeight":"504.60"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by inhibiting the production of pro-inflammatory cytokines and mediators, leading to a decrease in inflammation and immune response. This is achieved through the binding of betamethasone to glucocorticoid receptors, which then modulate gene expression and protein synthesis. As a result, betamethasone dipropionate aerosol spray is effective in treating various skin conditions characterized by inflammation and immune dysregulation.","oneSentence":"Betamethasone dipropionate aerosol spray is a topical corticosteroid that reduces inflammation and suppresses the immune system.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:22:58.149Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Severe skin conditions such as psoriasis, atopic dermatitis, and seborrheic dermatitis"}]},"trialDetails":[{"nctId":"NCT02416258","phase":"PHASE2","title":"A Psoriasis Plaque Test Trial With LP0113 Spray in Patients With Psoriasis Vulgaris (LP0113-1123)","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2015-04","conditions":"Skin and Connective Tissue Diseases","enrollment":50},{"nctId":"NCT02881346","phase":"","title":"Efficacy and Tolerability of Enstilar® in Daily Practice","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2016-09","conditions":"Plaque Psoriasis","enrollment":410}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Betamethasone dipropionate aerosol spray","genericName":"Betamethasone dipropionate aerosol spray","companyName":"LEO Pharma","companyId":"leo-pharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Betamethasone dipropionate aerosol spray is a topical corticosteroid that reduces inflammation and suppresses the immune system. Used for Severe skin conditions such as psoriasis, atopic dermatitis, and seborrheic dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}